Regiospecific halogenation of azacalix[1]arene[3]pyridines at the lower rim position of the benzene ring was achieved from their cross-coupling reaction with cost-effective alkali metal halides through the Cu(ClO(4))(2)-mediated aerobic aryl C-H activation, which gave structurally well-defined aryl-Cu(III) intermediates, and a subsequent C-X bond formation reaction under very mild conditions.

This review examines recent advances in asymmetric catalytic decarboxylative addition reactions which have become a powerful method to form CC and CX bond using relatively cheap and stable carboxylic compounds. In these reactions, new CC or CX bonds are formed with extrusion of carbon dioxide (CO2). Asymmetric decarboxylative addition reactions have become alternatives to traditional addition reactions. Various asymmetric reactions between carboxylic acids and unsaturated compounds are summarized. The challenges and opportunities of these reactions are discussed.magnified image

Environmentally friendly hypervalent iodine reagents are unusually effective promoters of asymmetric α-functionalization of carbonyl compounds. By using hypervalent iodine reagents, various substituents can be introduced into the α-position of carbonyl compounds. In the present review, we briefly survey the asymmetric α-functionalization of carbonyl compound reactions catalyzed by these hypervalent iodine reagents.

Regiospecific functionalization of tetraazacalix[1]arene[3]pyridines at the lower rim position of the benzene ring was achieved conveniently from their cross-coupling reaction with both aliphatic alcohols including chiral primary and secondary alcohols and phenol derivatives through the Cu(ClO(4))(2)-mediated aerobic aryl C-H activation, which gave structurally well-defined aryl-Cu(III) intermediates and a subsequent C-O bond formation reaction under very mild conditions.

Sulfenylation of C–H bonds for C–S bond formation under metal‐free conditions has become established as a powerful tool in organic chemistry. Various sulfenylation reagents such as thiols, disulfides, sulfinic acids, and so on have been employed for sulfenynlation reactions. In this review we mainly summarize the recent advances (2014 to the present) in this area and also discuss the mechanisms.