Sepsis is a substantial healthcare burden, and its management continues to be a major challenge. Prior studies demonstrate conflicting evidence regarding the utility of vitamin C in sepsis. This systematic review and meta-analysis aim to collect data among critically ill patients (sepsis/septic shock), comparing the efficacy of parenteral vitamin C with standard care.A literature review was conducted using databases including PubMed, Web of Science, Google Scholar, and the Cochrane Library to identify randomized controlled trials (RCTs) and observational studies comparing intravenous vitamin C alone or in combination with thiamine or glucocorticoids to the standard of care. We identified 11 RCTs and seven retrospective cohort studies. The primary outcome was 28-day mortality. Secondary outcomes included intensive care unit (ICU) length of stay, change in Sequential Organ Failure Assessment (SOFA) score, duration of vasopressor use, and duration of mechanical ventilation.A total of 18 studies with 4078 patients were included in our final analysis. Overall, we found no mortality reduction in patients treated with vitamin C compared to standard of care (odds ratio (OR) 0.92; 95% confidence interval (CI) 0.78 to 1.09; p = 0.34). Studies that reported a change in SOFA scores, ICU length of stay, duration of mechanical ventilation, or duration of vasopressor use did not show any significant difference between groups. Subgroup analysis with RCT versus observational studies and vitamin C dosage regimens did not show any difference.Among patients with sepsis or septic shock, treatment with vitamin C was not associated with a reduction in mortality, ICU length of stay, change in SOFA score, duration of vasopressor use, or duration of mechanical ventilation. Further studies are needed to demonstrate the potential role of vitamin C in the management of sepsis.

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Automated classification of text into predefined categories has always been considered as a vital method in thenatural language processing field. In this paper new methods based on Radial Basis Function (RBF) and Fuzzy Radial BasisFunction (FRBF) are used to solve the problem of text classification, where a set of features extracted for each sentencein the document collection these set of features introduced to FRBF and RBF to classify documents. Reuters 21578 datasetutilized for the purpose of text classification. The results showed the effectiveness of FRBF is better than RBF.

The Basel Committee on Banking Supervision (BCBS) has introduced Basel III which was initiated after the recent global financial crisis in an effort to strengthen the regulatory regime of the banking sector. Basel III has introduced several modifications such as added liquidity requirement ratios in addition to strengthening capital requirements. This paper examines the impact of Basel III regulatory framework on Islamic Finance from a theoretical point of view. Using content analysis, this study finds that the impact of Basel III on Islamic Finance is relatively smaller than conventional finance since their model does not support short selling and non-Shari'ah complaint derivatives and thus they are having this competitive advantage over their conventional counterpart. However, it is important to highlight that deep examination of Islamic Banks' nature, specifications, and the way they conduct business is required to identify issues not considered by the Basel III framework. As Islamic Banks will not be able to fully adopt Basel III framework without any modifications that are in line with their specifications and nature. Thus, recommending IFSB to adapt these new requirements and issue new standards by considering Islamic finance industry when doing so. There is also a need for a robust infrastructure for Islamic financial institutions for their sound liquidity and smooth functioning, which will include development of Islamic money market and securities market. In addition, there is need for innovating new Shari'ah compliant products for Islamic financial institutions instead of just mimicking conventional products.

Steganography is a technique to hide a secret message within a different multimedia carrier so that the secret message cannot be identified. The goals of steganography techniques include improvements in imperceptibility, information hiding, capacity, security, and robustness. In spite of numerous secure methodologies that have been introduced, there are ongoing attempts to develop these techniques to make them more secure and robust. This paper introduces a color image steganographic method based on a secret map, namely 3-D cat. The proposed method aims to embed data using a secure structure of chaotic steganography, ensuring better security. Rather than using the complete image for data hiding, the selection of the image band and pixel coordination is adopted, using the 3D map that produces irregular outputs for embedding a secret message randomly in the least significant bit (LSB) of the cover image. This increases the complexity encountered by the attackers. The performance of the proposed method was evaluated and the results reveal that the proposed method provides a high level of security through defeating various attacks, such as statistical attacks, with no detectable distortion in the stego-image. Comparison results ensure that the proposed method surpasses other existing steganographic methods regarding the Mean Square Error (MSE) and Peak Signal-to-Noise Ratio(PSNR).