Guillain-Barré syndrome (GBS) is a rare, acute immune-mediated polyradiculoneuropathy that accounts for an estimated 100,000 new cases annually worldwide. The typical clinical manifestations of the disease are progressive, ascending paralysis, classically involving bilateral upper and lower extremities. In most patients, the acute onset of neurological symptoms is preceded by an infectious respiratory or gastrointestinal illness. The case is presented of a 50-year-old man who was transferred to an intensive care unit from the Department of Neurology, due to a worsening state of bilateral weakness of limbs, with symptoms of respiratory failure and hemodynamic instability. Guillain-Barré syndrome was diagnosed in the previous clinic on the basis of the typical symptoms and results of cerebrospinal fluid, in which albuminocytological dissociation was detected. Furthermore, two weeks previously, the patient had been infected with COVID-19.
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Autoimmune anti-N-methyl-D-aspartate (NMDA)-receptor encephalitis as a rare cause of the complex psychiatric and neurologic manifestations. A case report and review of the literature. J Pre-Clin Clin Res.
Meningococcal meningitis is an inflammation of the meninges caused by Neisseria meningitidis. Clinically, meningococcal meningitis does not differ from other bacterial meningitis. Initially, the symptoms of the disease may be non-specific, such as fever, muscle pain, and weakness, only later do the symptoms typical of meningitis appear. Adolescents and adults have a lower incidence of neck stiffness and altered consciousness than younger patients. The disease is characterized by a rapid onset and progression of symptoms within a few hours. The detection of Neisseria meningitidis in the cerebrospinal fluid allows for the correct diagnosis and appropriate treatment. Antibiotics reduce mortality in meningococcal disease by up to five times. The case is presented of a young adult patient with a history of viral meningitis in childhood who was hospitalized for severe meningococcal meningitis and successfully treated.
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