Currently, diff erent physiotherapy methods are widely used in medicine. One of these methods is ultraviolet (UV) treatment. It is frequently used in healthcare practice as a disinfectant. However, it has a wide range of biological eff ects.   The aim of this study is to summarize known eff ects of ultraviolet radiation and evaluate applications of UV treatment in medicine, especially in dentistry.   Methods. We conducted literature review using PubMed, Google School, eLibrary, РИНЦ, UpToDate, Elsevier, Scopus databases. 65 articles were analyzed during the research. The study is divided into 4 sections describing biological eff ect of UV and its usage in disinfection, diagnosis and treatment.   Results. The study confi rms that UV is an eff ective method used for treating somatic and dental diseases. The results show potential benefi ts of UV application as an additional antiseptic and disinfectant that has very few side effects.