Psychological stresses, personal turmoil, and social unrest of contemporary life has a significant detrimental effect on human nervous system. Mental health protection, timely diagnosis of mental illness, and rehabilitation and information support provide the necessary basis for efficacious medical treatment. In addition to somatic health protection, these problems are of considerable social importance.Psychophysiological examination of normal and pathological activity of the higher nervous system (HNS) is an effective instrumental method for monitoring working capacity and physiological state of patients. Such examination allows HNS characteristics to be assessed at the level of the entire behavioral pattern, rather than through individual behavioral events.Analysis of some scientific concepts [1, 2, 5] and our own experience in the development and use of psychophysiological devices (psychoengineering concept [31) has given rise to a number of principles designed to facilitate the development of medical and psychophysiological devices [4]. 1. Examination procedure should be based on an experimental model of consistent goal-oriented behavior with repeated basic stages of afferent synthesis, decisions on locomotor behavioral event, and evaluation Of its result. Each further afferent synthesis and decision making event depends on the results of the previous behavioral event.2. Results of examination should represent both cumulative characters and sequential organization of behavioral quanta and their temporal parameters.3. Examination hardware should be sufficiently flexible to implement various functional combinations. Each specific device should be able to isolate specific mechanisms of higher nervous actiwty and to assess it by individual characters and various combinations of the characters.A new generation of medical hardware has been developed and introduced into serial production on the basis of new medical and physiological concepts. The most effective and typical examples of such hardware are considered in the present work.A computer system for psychophysiological examinations was designed to implement various automatic techniques of psychological and psychophysiological examination of the human HNS in normalcy and in pathology.This system provides automatic quantitative evaluation of perception, attention, memory, psychomotor characteristics, etc. The range of available techniques can be extended and adapted to specific problems.A special personal computer terminal for monitoring sensomotor coordination and tremor implements procedures for measuring static and dynamic tremor and visual and audiomotor coordination (with closed eyes).The software allows implementation o[ various modes of automatic examination (including examination with audio and visual feedback), adjustment of examination modes, calculation, analysis, and archiving of examination results.A special medical physiological personal computer terminal for assessing stability of a patient's center of gravity can be used in orthopedics, neurology,...

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The study was undertaken to examine the specific features of the lipid spectrum in patients with metabolic disorders in the absence or presence of arterial hypertension (AH) and type 2 diabetes mellitus (DM) The study covered 176 patients with metabolic disorders, 138 patients were diagnosed as having AH, of them 39 patients had type 2 DM Clinical and laboratory studies involved the estimation of the body mass index, waist/hip ratio, and lipid spectrum All the patients were divided into 3 groups I) 38 without AH and type 2 DM, 2) 99 with isolated AH without type 2 DM, 3) 39 with AH and type 2 DM The higher severity of abdominal obesity was associated with enhanced dyslipidemia atherogemcity The development of AH m the presence of metabolic disorders was accompanied by higher total cholesterol levels, which may be considered as aggravated endothelial dysfunction Its concurrence with type 2 DM was attended by transformation of metabolic to diabetic dyslipidemia The study has yielded a new index that characterizes dyslipidemia atherogemcity in patients with metabolic disorders

The work carried out by analyzes of the literature data on assessing the severity of acute pancreatitis and predicting its course and mortality. A comparison of traditional point scales for assessing the severity of AP was made.As a result of a comparative analysis, it was found that the most objective instrumental method for diagnosing acute pancreatitis and its complications was MSCT with the determination of the CT index of severity. Balthazar scale allows assessing the severity of the disease and forming a prognosis for the development of complications. However, computed or magnetic resonance imaging with intravenous contrast enhancement allows an accurate assessment of the severity of the disease not earlier than 72 hours and has some contraindications.Estimating and predictive systems Ranson, APACHE, Krasnorogov, Bozhenkov systems, Pugaeva and Achkasova, BISAP and HAPS allow identyfying the severity of the clinical course of acute pancreatitis, have a high sensitivity, but at the same time require significant time and resources for execution. Glasgow-Imrie, SAPS, MODS, and SOFA scales mainly calculate mortality and degree of multiple organ failure in critically ill patients; these severity assessment systems are not specific for patients with acute pancreatitis.The optimal scale for assessing the severity of AP should allow assessing the patient's condition and prognosis from the moment of admission to the outcome of the disease. The practicing surgeon will be interested in an affordable, inexpensive, easy-to-use system for determining the severity of acute pancreatitis. For surgeons, the time factor plays a key role in determining tactics, and, therefore, improves the prognosis of the disease.