A cohort cross-sectional study of the attitude of the population to vaccination against coronavirus infection COVID-19 was carried out using a specially designed questionnaire for mass filling, located on Internet resources 2 months after the start of mass vaccination in Russia. A total of 4172 people were examined at the age from 18 to 81 years. Among the respondents, there were different tendencies in relation to vaccination. Of the total sample, 35.7% of respondents consider vaccination useful, 32.2%—doubt its effectiveness, 8.7%—consider vaccination unnecessary, 12.2%—dangerous, indifference to vaccination was formed in 5.9% of respondents. They indicated that they do not plan to be vaccinated, 30.8%, postpones their decision until more remote data on the results and effectiveness of vaccination are obtained—34.7%, were vaccinated at the time of the study—12.2%. Young people are less focused on vaccination than middle-aged and older people. Among the factors that are associated with the attitude towards vaccination are age, gender, education, fear of possible complications, fear of contracting a coronavirus infection, concern for the health of their loved ones, anxiety about the current situation with coronavirus in general. The reports of scientists, doctors and experts in this field are essential for shaping attitudes towards vaccination. The study results should be considered as the targets for vaccination behavior improvement psychosocial interventions for different social and age population groups

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The article provides an economic and statistical review of the structural changes in the economy of the Amur Region from 2004 to 2016. An analysis of regional statistics on the industrial structure of gross value added (GVA) over the period under review allowed the author to identify quantitative parameters identifying economic activities that determine the characteristics of the modern economy of the region, and those that have not been developed.Based on statistical calculations, it was concluded that leading economic activities in the Amur Region are «Transport and Communication», «Mining and quarrying», «Wholesale and retail trade».The primary objective of the study was to determine the degree of intensity of structural shifts in the regional economy and identify the main trends of its development. The «absolute» gains and growth factors of the relative structural components of the GVA for the Amur Region for the period under review were calculated to characterize these structural changes.According to the author, the calculations indicate the absence of a positive transformation in the structure of the regional economy. Thus, the intensive development of the commodity sectors of the economy continues, and the low growth rates of the manufacturing industries are noted. To carry out a summary assessment of structural changes in the regional economy, the author has calculated the linear and quadratic coefficients of the «absolute» structural changes. The results provide an opportunity to more accurately identify critical areas for investment, as well as support those economic activities that will allow the region to maximize its potential benefits.

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