Amyotrophic lateral sclerosis (ALS) is

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Methods which on one hand can ensure the patient's mobility and on other hand activate afferents inputs are the main in rehabilitation treatment. Recent studies has shown that plasticity is structural base of recovery after central nervous system injury. Reorganization of cortical areas and increase of preserved structures functional effectiveness (intensification afferent input) are an anatomical basis of plasticity. However, sensory correction methods, without accounting of functional condition of patients, can lead to the formation of pathological symptoms: spasticity, hyperreflexia, etc. So the main aim is to study adequate management of the neuroplasticity process. This problem cannot be solving without modern methods of neuroimaging and brain mapping. The new approach for study cortical mechanisms of neuroplasticity, responsible for locomotion, was developed in the present study. This approach is complex use of functional magnetic resonance imaging (fMRI) and navigation transcranial magnetic stimulation (nTMS). It was showed that vast fMRI activation area in the first and the second sensorimotor area emerges with passive sensorimotor paradigm using that imitate backing load during walking. The mechanical stimulator footsteps backing zones "Corvit" uses for create this paradigm, nTMS examination, which used after fMRI, help localize the motor representation of muscles which control locomotion more accurately. We guess that new approach can be used for neuroplasticity process study and assessment of neuroplasticity changes during rehabilitation for restore and correct the walking.

In [5], an analytical formula for determining the density is obtained in the case when the external gravitational fi eld of the body is zero, it is absent. In this paper we continue the research started in [5]. The inhomogeneous linear integrodifferential equation of Geophysics for determination of density of the gravitating body is received. It is proved that with the help of this equation it is possible to obtain the solution of internal and external boundary value Dirichlet problems and to determine the density of the gravitational body. However, in our opinion, much more important is the fact that the density cannot be determined in other ways, because it is impossible to penetrate into the body.