nennost xronicheskoj serdechnoj nedostatochnosti v Evropejskoj chasti Rossijskoj Federaczii dannye EPOXA-XSN (chast 2) [Prevalence of chronic heart failure in the European part of the Russian Federation-Data of AGE-CHF (part II)].

Aim. To study the association of some gynecologic history data in hypertensive women with abdominal obesity. Methods. A cohort of 315 women aged 21-59 years, including 53 healthy volunteers with normal blood pressure, 63 female patients with prehypertension and 197 hypertensive women, was examined. The mean age of hypertensive women was 47.0±7.0 years. Patients with symptomatic hypertension were excluded from the study. The patients were questioned about gynecologic history data (the number of pregnancies, abortions, miscarriages, history of gestational hypertension) and anthropometry. Patients were divided to 2 groups according to presence (137 female patients, mean age 47.8±6.3 years) or absence (178 female patients, mean age 44.4±7.3 years) of abdominal obesity. Results. There was a significantly higher number of women who had had pregnancies (97.3 versus 83.0%), deliveries (94.7 versus 76.5%), including two and more deliveries (69.9 versus 38.2%), and two and more abortions (64.6 versus 34.0%) among hypertensive women with abdominal obesity compared to non-obese women with normal blood pressure; higher mean rates of pregnancies, deliveries and abortions, more frequent history of gestational hypertension (51.3 versus 14.9%) were revealed as well. Conclusion. The combination of abdominal obesity and hypertension in women aged 21-59 years is associated with higher number of previous pregnancies, abortions, miscarriages and pregnancies, abortions, miscarriages, and history of gestational hypertension.

Aim. To study the distribution of cardiovascular risk factors, target organ damage, associated clinical conditions and to stratify the 10-year risk of arterial hypertension complications in menopausal females depending on presence of inappropriately high left ventricular mass. Methods. 107 females from city of Kazan aged 42-59 years entered the study, including 11 women with normal blood pressure, 16 patients with high normal blood pressure, and 80 patients with hypertension according to All-Russia scientific Society of Cardiologists classification (2010) with disease duration of 0-34 years. Mean age of patients with hypertension was 51.4±4.0 years. Patients with secondary hypertension were excluded from the study. All patients underwent a questionnaire survey, physical examination, biochemical blood test, ECG, echocardiography, and cervical extracranial vessel ultrasonography. Actual left ventricle mass was calculated according to R.B. Devereux et al. (1977) and was adjusted to the body surface area. Proper left ventricle mass was defined by G. Simone et al. (1998). Disproportion coefficient was calculated as a ratio of actual left ventricle mass to proper left ventricle mass. Left ventricle hypertrophy was diagnosed using the Sokolow-Lyon index and left ventricle mass index ≥ 110 g/m2 (Echo-signs of left ventricle hypertrophy). Results. In menopausal women, inappropriately high left ventricular mass was associated with significantly (р 0.05, Fisher exact test) higher frequency of obesity, especially its abdominal type, as well as target organ damage, including Echo-signs of left ventricle hypertrophy, very high added 10-year risk of developing arterial hypertension complications. It was also associated with significantly (р 0.05, the U-criterion) higher mean values of waist circumference, waist to hip circumference ratio, body mass index, total number of damaged target organs and 10-year risk for developing arterial hypertension complications. Conclusion. Distinguishing the patients with inappropriately high left ventricular mass among menopausal women is important for planning the measures to prevent cardiovascular events.

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Aim. To assess the cardiovascular risk in women of reproductive age, depending on the presence of gestational arterial hypertension in the anamnesis. Methods. Examined were 25 practically healthy volunteers with normal blood pressure, 33 patients with high normal blood pressure and 77 women with arterial hypertension (Classification of the All-Russian Scientific Society of Cardiologists, 2010) with a history of arterial hypertension of 0.5-24 years. The average age of patients with arterial hypertension was 40.8±4.5 years. All examined individuals were divided into two groups depending on the presence of gestational arterial hypertension. Determined were the group averages and grades (in percent) of the studied factors. Results. Among women of the reproductive age gestational arterial hypertension was significantly more common in patients with arterial hypertension compared to women with normal levels of blood pressure (62.3 vs. 16%, p 0.001 by χ2 criteria). In the group of patients with arterial hypertension who have gestational arterial hypertension, compared with those individuals with normal blood pressure, who have gestational arterial hypertension significantly more ofter (p 0.05, Fisher’s exact test) seen was the abdominal type of obesity (54.1 vs. 0%). In the group of patients with arterial hypertension who have gestational arterial hypertension, compared with individuals with normal blood pressure without gestational arterial hypertension significantly more often (Fisher’s exact test) recorded was a family history of cardiovascular disease (inxcluding arterial hypertension), obesity, especially the abdominal type; revealed were significantly (by the U criteria) higher mean values of waist circumference, waist circumference relationship to hip circumference, body mass index, total cholesterol level. A significantly (p 0.01, Fisher’s exact test) greater proportion of individuals with very high additional risk of developing complications of hypertension in the next 10 years was noted in the group of patients with arterial hypertension and gestational arterial hypertension compared to patients with high normal blood pressure and gestational hypertension (37.5 vs. 0%). Conclusion. In women of reproductive age gestational arterial hypertension is a specific risk factor for subsequent arterial hypertension that is associated with significantly greater frequency of obesity, especially the abdominal type, very high additional risk of complications of arterial hypertension, as well as significantly higher mean values of waist circumference, ratio of waist circumference / hip circumference, and total cholesterol level.