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Objective. Our objective was to study the prevalence of toxoplasmosis among various groups of population in the Omsk Region. Materials and methods. We analyzed statistical data and the results of our own serological tests carried out in 2000–2017. Antibodies to Toxoplasma were determined in 1,926 people (769 citizens and 1,157 villagers). The blood serum was used as the test material. For the detection of IgG and IgA antibodies to toxoplasma, we used locally produced ELISA test systems (“Vector-Best”, Novosibirsk). Results. Antibodies to toxoplasmas were found in residents of all landscape areas of the Omsk Region. In the northern parts of the forest zone, 45.9 % of people had antibodies to toxoplasma; in the southern steppe zone, 64.6 % of people had those antibodies. Urban residents were infected in 17.7 % of cases. There were significant age-related differences in toxoplasma infection in the population of the Omsk Region. The maximum rates of invasion in older age groups were more than 50 % among urban residents and over 70 % in rural areas. Rates of seropositivity of rural children under 15 were 5 times higher than those in urban children. Serological markers of toxoplasmosis were detected in 52.8 % of rural women of childbearing age and in 33.9 % of urban women. Сonclusion. The research results indicated the unfavorable epidemic situation for toxoplasmosis in the Omsk Region. Taking into account the risk of infection for people with immunodeficiency and pregnant women and the possibility to reactivate the invasion even in an immunocompetent organism, it is necessary to study distinctive features of the toxoplasmosis epidemic process in different areas of the Omsk Region and to develop regulatory and procedural documents on prevention of Toxoplasma infection in the population.

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Aim. Analysis of the epidemiological and epizootological situation in the Omsk region over the past 12 years (2008)(2009)(2010)(2011)(2012)(2013)(2014)(2015)(2016)(2017)(2018)(2019) and identification of factors affecting the epidemic manifestations of brucellosis in modern conditions on the territory of the Omsk region.Material and methods. The data of the official registration of infectious diseases in the Russian Federation, accounting documents of the Office of Rospotrebnadzor, Rosselkhoznadzor, the Main Veterinary Directorate of the Omsk Region for 2008-2019 are analyzed. A retrospective epidemiological analysis was carried out over a 12 year period. Graphic data was obtained using Microsoft Excel 2007.An analysis of 91 stationary maps of patients with newly diagnosed brucellosis was carried out.Results. Total for 2008-2019 95 cases of newly diagnosed brucellosis in humans were reported. In the study period, registration of chronic brucellosis with a gradual onset (44 cases) and residual brucellosis (13 cases) prevailed in people. Acute brucellosis was recorded in 22 cases, subacute in 8 cases. Examination of contacts in dysfunctional foci of brucellosis revealed 8 cases of latent brucellosis. Among the cases of brucellosis, residents Contribution: design the study, wrote the manuscript.