In the frame of Multicenter observational study ECVD-RF (Epidemiology of Cardiovascular Diseases and their Risk Factors in Regions of Russian Federation) by the unique protocol the investigation of representative selections of adult population at the age of 25-64 y.o. of 11 regions RF (n=18305, including males, n=6919 and females n=11386): Volgograd, Vologda, Voronezh, Ivanovo, Kemerovo, Orenburg, Samara, Tomsk, Tyumen, Saint-Petersburg and Northern Osetia-Alania. The prevalence of the following risk factors (RF) of cardiovascular diseases is evaluated: high blood pressure — 33,8%, obesity — 29,7%, high total cholesterol — 57,6%, high glucose level or diabetes — 4,6%, smoking (tobacco consumption) — 25,7%, insufficient (low) level of physical activity — 38,8%, excessive salt consumption — 49,9% and insufficient vegetables and fruits consumption — 41,9%. Gender differences and an increase with the age of the parameters mentioned are described.The absence of a epidemiologic monitoring system at the Federal level leads to an impossibility of clear conclusions on the RF dynamics in Russian population. While comparing the ECVD-RF study with previous epidemiological studies we can just cautiously suppose the existence in 21st age of negative dynamics of one RF (obesity, dyslipidemia) and positive dynamics of the others (smoking).
Aim. To assess the prevalence of wide QRS complex (≥110 ms) among the population, depending on sex, age, place of residence (urban or rural area), the presence of obesity and cardiovascular disease.Material and methods. The analysis was based on the ESSE-RF study (n=17,364, men — 38%). Twelve-lead resting electrocardiography (ECG) data from the regions participating in the study were analyzed according to the Minnesota code manual. Patients were divided into groups of QRS <110 ms and ≥110 ms (wide QRS).Results. QRS groups did not differ in heart rate and age. The prevalence of wide QRS complex in the population amounted to 17,2%. Men were likely to have wide QRS than women (18,5% and 16,2%, respectively, p<0,0005) due to the increased frequency of “preblock” QRS duration (110-119 ms; 12,3% vs 10,9%, respectively, p<0,025). The prevalence of QRS≥120 ms in the sex groups was the same, almost 7%. The prevalence of widened QRS in the population significantly exceeded other unfavorable prognostic ECG indicators, such as major ECG abnormalities, conduction disorders, abnormal Q wave (QS). The prevalence of wide QRS complex increased with age from 11,1% to 19,2, (p<0,001). The highest increase in prevalence of wide QRS complex was observed after 55 years; nondynamic periods were recorded in men from 25, and in women from 35 to 54 years. In contrast to women, the prevalence of wide QRS in men did not depend on the place of residence (18,6% in urban and 18,3% in rural areas); in rural women this parameter was observed as often as in men. This may indicate a more severe epidemiological situation of car - diovascular disease in rural residents. Obesity, high blood pressure, and a history of coronary artery disease were more common in the group of wide QRS complex.Conclusion. For wide QRS complex, the same age and sex relationships are cha - racteristic as for the basic routine ECG indicators. The prevalence of wide QRS in the population exceeds major ECG abnormalities, conduction disorders, abnormal Q wave (QS). In rural residents, the increased prevalence of wide QRS is probably due to the greater prevalence of obesity and hypertension.
Цель. Оценить 10-летний риск потенциального развития сахарного диабета 2 типа (сД2) в российской популяции с помощью шкалы fINDrIsC и изучить его ассоциации с социально-демографическими и поведенческими факторами по данным эпидемиологического исследования эссе-Рф. Материал и методы. В работе использованы данные многоцентрового исследования (эпидемиология сердечно-сосудистых заболеваний в различных регионах Российской федерации: эссе-Рф). Всего было обследовано 21923 человек 25-64 лет, из которых у 1045 человек (мужчин-3,76% и женщин-5,39%) отмечался сД в анамнезе. В окончательный анализ включено 20878 лиц (8058 мужчин и 12820 женщин) без сД, которым определялся 10-летний риск развития сД2 с помощью шкалы fINDrIsC (The fINnish Diabetes rIsk sCore). Уровень риска и вероятность развития сД2 оценивался по полученной сумме баллов на основании ответов на вопросы. Кроме того, анализировались ассоциации с образованием, семейным положением, местом жительства, достатком, а также статусом курения и потребления алкоголя. Результаты. Порог высокого риска сД2 для нашей популяции составил ≥12 баллов, площадь под кривой (AUC)-0,76, что соответствует хорошему качеству модели. Распространенность высокого риска по российским критериям составила 20,4%. Многофакторный анализ, продемонстрировал, что после коррекции по возрасту и региону высокий риск сД2 у мужчин ассоциируется с отказом от курения (отношение шансов (ОШ) 1,34; 95% доверительный интервал (ДИ) 1,14-1,58; р=0,0004) и употреблением алкоголя (ОШ 2,01; 95% ДИ 1,48-2,71; р=0,0001), а у женщин с низким доходом, низким образовательным уровнем и у замужних. Заключение. средний уровень баллов по fINDrIsC составил для всей популяции 6,5±0,03, а абсолютный риск 5,3%. Выявлены ассоциации высокого риска сД2 (≥12 баллов) с поведенческими факторами у мужчин и с социальнодемографическими показателями у женщин.
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