In this paper, experiments with water-based solutions of some organic compounds, which demonstrate non-Ostwald behavior have been described. Small-volume droplets demonstrate higher stability during evaporation and crystallization in comparison with larger ones, such an effect has been previously described only for water-based solutions of inorganic salts. It has been shown that non-Ostwald behavior has the same thermodynamic nature with Ostwald ripening and could occur in dispersed systems of a complicated chemical composition. Peculiar realization of such phenomena driven by surface activity of organic compounds in water solutions has also been described. The studied regularities could be used to obtain solutions of organic and bioorganic substances with concentrations significantly higher than their solubility limits under normal conditions as well as to reproduce narrow size distributions of droplets in various spray technologies.