Клинико-патогенетические особенности церебрального инсульта у больных с новой коронавирусной инфекцией (COVID-19) 1 Санкт-Петербургское государственное бюджетное учреждение здравоохранения «Городская многопрофильная больница ¹ 2»,

The objective of the study was to assess the effectiveness of local injection therapy in patients with lumbosacral pain during medical blockades.Methods and materials. The results of treatment of compressive lumbosacral radiculoischemia were studied in prospective trial with placebo control. One of the most valuable criteria of medical effectiveness was decrease of pain intensity by visual analog scale and McGill’s questionnaire. 58 patients were included in the study. Comparison between the groups was carried out depending on the treatment: first group was treated with combination of anesthetic with corticosteroids (diprospan), second group – only anesthetic. Rate of pain decrease was assessed during the first day and for 14 days.Results. In patients with lumbosacral pain treated with combination of anesthetic with corticosteroids, decrease of pain intensity was obtained by visual analog scale and McGill’s questionnaire point. Local corticosteroids use was the most effective with effect in a short time – during the first 24 hours.Conclusion. Short course of local injection therapy had high effectiveness in patients with lumbosacral pain syndrome.

Purpose: The article covers issues related to providing personal protection equipment (PPE) for medical staff exposed to coronavirus (or similar infection) in the face of global pandemic and insufficient supply of infectious hospitals with disposable overalls. As many polymeric materials used to make such overalls do not feature required thermal stability and consequently they cannot be treated with heat disinfection, radiation treatment of protective overalls with electron accelerators for the purpose of their reuse was considered. Due to rich experience in addressing the issues of providing high-efficient, physiologically acceptable PPE for the personnel of radiation and chemical hazardous facilities, in particular during Chernobyl nuclear disaster elimination, the Laboratory of PPE for the Personnel of Hazardous Production Facilities, Burnasyan Federal Medical Biophysical Center, could extend methods of assessment and techniques of human protection against high-toxic substances to establishment of protection against microbiological threats. Results: The article provides results of analysis and tests of materials for overalls and respiratory PPE currently in use. Based on the material tests for radiation stability, air permeability, liquid penetration and protective properties with respect to aerosols, recommendations for improvement of efficiency and comfort of the PPE suite have been developed. Conclusion: The study showed feasibility of reusing overalls after radiation treatment. However, such treatment is appropriate only in periods of major emergencies during peacetime and wartime, when there are no production capabilities for manufacturing of new products. Location of the irradiation facility in the vicinity of consumers (e.g. medical institutions) is a prerequisite for this treatment. It should be emphasized that radiation treatment must be performed under strict supervision of accredited test facilities. Further research is required for development and enhancement of PPE and system of its application. This will allow to make longtime wear of PPE more comfortable without sacrificing its protective efficiency and develop a manual on product-specific radiation treatment.

Петербургский клинический научно-практический центр специализированных видов медицинской помощи (онкологический)», Санкт-Петербург, Россия РЕЗЮМЕ В обзоре представлены данные о классификации, механизмах развития и клинических проявлениях нейротоксичности. Проанализированы основные особенности нейротоксичности при использовании таксанов, включая кумулятивные дозы. Рассмотрены доказанные методы лечения и профилактики нейропатии, вызванной цитостатическими препаратами.

This paper presents the experience of practical use of the technology of computer stabilography with biological feedback in rehabilitation of patients suffering from lumbar-sacral dorsopathies and diagnosed large lumbar hernias. The data of high diagnostic and rehabilitation effectiveness of stabilometry systems was obtained during the 14-days observation period of 16 patients with clinical manifestations of L5-S1 radiculopathy and dorsalgia. The method was used in assessment of neurology deficit and secondary myotonic disturbances. The decrease of intensity of pain and recovery of axial balance and coordination were achieved. As a statistically significant improvement of the equilibrium, the Romberg’s coefficient was decreased from 670 to 295% (p<0.05) during the drug therapy and 10 trainings on stabiloplatform. The achieved data show the improvement of segmental motor and sensory functions, decrease of disturbances in statics and dynamics of vertebral column in patients with radicular syndrome and large hernias after the rehabilitation course with the application of the technology of computer stabilometry.