Abstract. The classic approach to calculate the electrostatic field penetration, from the Earth's surface into the ionosphere, is to consider the following equation ∇· σ ·∇ =0 whereσ and are the electric conductivity and the potential of the electric field, respectively. The penetration characteristics strongly depend on the conductivities of atmosphere and ionosphere. To estimate the electrostatic field penetration up to the orbital height of DEMETER satellite (about 700 km) the role of the ionosphere must be analyzed. It is done with help of a special upper boundary condition for the atmospheric electric field. In this paper, we investigate the influence of the ionospheric conductivity on the electrostatic field penetration from the Earth's surface into the ionosphere.We show that the magnitude of the ionospheric electric field penetrated from the ground is inverse proportional to the value of the ionospheric Pedersen conductance. So its typical value in day-time is about hundred times less than in night-time.

Biomedical applications of magnetic nanoparticles under the influence of a magnetic field have been proved useful beyond expectations in cancer therapy. Magnetic nanoparticles are effective heat mediators, drug nanocarriers, and contrast agents; various strategies have been suggested to selectively target tumor cancer cells. Our study presents magnetodynamic nanotherapy using DNA aptamer-functionalized 50 nm gold-coated magnetic nanoparticles exposed to a low frequency alternating magnetic field for selective elimination of tumor cells in vivo. The cell specific DNA aptamer AS-14 binds to the fibronectin protein in Ehrlich carcinoma hence helps deliver the gold-coated magnetic nanoparticles to the mouse tumor. Applying an alternating magnetic field of 50 Hz at the tumor site causes the nanoparticles to oscillate and pull the fibronectin proteins and integrins to the surface of the cell membrane. This results in apoptosis followed by necrosis of tumor cells without heating the tumor, adjacent healthy cells and tissues. The aptamer-guided nanoparticles and the low frequency alternating magnetic field demonstrates a unique non-invasive nanoscalpel technology for precise cancer surgery at the single cell level.

Abstract.It is well known that lithospheric electromagnetic emissions are generated before earthquakes occurrence. In our study, we consider the physical penetration mechanism of the electric field from the Earth's surface, through the atmosphere-ionosphere layers, and until its detection in space by satellites. A simplified approach is investigated using the electric conductivity equation, i.e., ∇(σ · ∇ ) = 0 in the case of a vertical inclination of the geomagnetic field lines. Particular interest is given to the conductivity profile near the ground and the electric field distribution at the Earth's surface. Our results are discussed and compared to the models of Pulinets et al. (2003) and Denisenko et al. (2008). It is shown that the near ground atmospheric layer with low conductivity decreases the electric field penetration into the ionosphere. The model calculations have demonstrated that the electric field of lithospheric origin is too weak to be observed at satellite altitudes.