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The article contains data, characterizing results variations of specific laboratory HIV-infection diagnostics after ultrasonic exposure directed at biological objects of blood serum. Detailed consideration of biophysical and medical aspects of tissues response on ultrasonic exposure, including immune complexes dissociation, accompanied by antibodies and antigens appearance, previously being in bound state and inaccessible for revealing by laboratory methods was carried out. On the example of HIV-infection good perspectives of ultrasonic application for immune complexes disintegration in laboratory diagnostics is demonstrated.

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