Aim. To assess clinical effectiveness of axillary region myoplasty using pectoralis minor muscle flap as an achievable and easy in technical performance method for seroma prevention after radical mastectomy.Methods. 545 patients aged 45 to 65 years (mean age 42.34±0.62 years) with stage I-II breast cancer, who were followed up from 2006 to 2014, were examined. Patients were divided into two groups: the main group included 256 women who underwent Patey’s mastectomy combined with axillary region myoplasty using pectoralis minor muscle flap (using the method developed by the authors in 2005-2006, and patented in 2010) and the control group consisted of 289 patients with Patey’s mastectomy.Results.The total seroma volume for 14 days in patients of the main group was 76.3% less than that in patients without myoplasty (pConclusion. Axillary region myoplasty with pectoralis minor muscle is an effective method of prevention, leading to a decrease in the seromas volume and duration in the postoperative period, as well as hospitalization period reduction.

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