This article contains a review of the literature on the issue of migraine and glaucoma interrelation. At the present time, despite the controversial nature of the results of global research, we can talk about an authentic increase of glaucoma risk in patients with a history of migraine. It is assumed a significant role of the primary vascular dysregulation in the pathogenesis of both diseases. Also we considered the issue of increasing the risk of angle-closure glaucoma during a migraine therapy with anticonvulsant called «Topiramate».