Use of the method liquid-based cytology with next immunocytochemical study of endometrium is expedient for the differential diagnosis of endometrial pathology processes. The level of the gene PTEN and steroid receptors expression is higher in cases of simple hyperplasia and hyperplasia without atypia. Increase of the markers p53 and Ki67 expression was found only by atypical endometrial hyperplasia. Positive reaction on CD138 determines the inflammatory process.

The paper considers modern approaches to the study of the method of cytological changes of Dysplastic squamous epithelium of the cervix, definition of pathogenetic treatment with the aim of preventing invasive cervical cancer: reducing morbidity and mortality