The upper part of the sedimentary cover within the East Siberian Sea shelf comprises Cenozoic clinoform deposits, which accumulated in passive continental margin settings. In the Eastern Arctic, the productivity of clinoform deposits has been proved on the Alaska North Slope and in the Beaufort–Mackenzie Basin. Considering that Cenozoic clinoform deposits are widely represented in the Russian part of the Eastern Arctic, they undoubtedly attract considerable interest from the standpoint of hydrocarbons prospecting. However, despite increasingly closer attention to this interval of the sedimentary section, it is still poorly understood due to its complicated geology. The lack of drilled wells in the region imposes a considerable limitation on an understanding of sedimentary basins development. In this situation, geophysical data become the primary source of information for building geologic models in the Russian sector of the Eastern Arctic. An assessment of hypothetical Cenozoic petroleum systems of the East Siberian Sea is the main objective of this paper. It is to be said research performed under high uncertainty of input data. The results obtained from basin analysis and numerical modeling indicate the possibility that an active petroleum system may exist in the Cenozoic sedimentary wedge of the East Siberian Sea. The outlook for the clinoform complex largely depends on the source rock maturity, i.e., higher prospects should be expected in areas where the prograding wedge has maximum thickness. Considering all factors (reservoir quality prediction, proximity to a hydrocarbon kitchen, timing), the Eocene–Oligocene part of the sedimentary section appears to offer the greatest promise within the study area. Here, predominantly oil accumulations may be expected at a depth of 2.5–3.5 km below sea bottom.
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