Central pontine myelinolysis (CPM) is a concentrated, symmetric, non-inflammatory demyelination within the central basis pontis. In 10 % of patients with СРМ, demyelination also occurs in extrapontine regions: the mid brain, thalamus, basal nuclei, and cerebellum. Demyelination occurs in regions of compact interdigitation of white and gray matter as a result of cellular edema, which is caused by fluctuating osmotic forces, results in compression of fiber tracts. The most frequent cause of abrupt change in osmotic pressure is the rapid sodium correction of prolonged hyponatremia. In case that we report, there is a combination of central pontine and extrapontine myelinolysis, which occurs in 71-year-old woman owing to rapid sodium correction of prolonged hyponatremia which by turn developed due to salt-free diet, improper antihypertensive therapy and overheating. The diagnosis was confirmed by magnetic resonance imaging (MRI). The treatment led to significant decrease of neurological deficit.

The necessity of special automated systems creation for the effective organization of industrial enterprise processes is substantiated. The effectiveness indicators of the production planning process are defined and the criteria for their evaluation are determined. The results of an automated planning system introduction at several instrument-making enterprises are presented, according to which an improvement in all effectiveness indicators was obtained, namely: the number of mistakes in the data collection subprocess was reduced by 85%, the time of production plan creation was reduced to 1 minute, the mistakes of plan creation process were completely eliminated, the time of plan and it versions assessment was reduced by 60%, and the timing of the studied planning subprocesses was completely observed.

Analysis of production planning process was done: model of process described with applying of IDEF0 methodology, problems of production planning process listed and also risks of developed process identified. Risk assessment conducted by two methods – critical level ranking by experts and FMEA. Calculation results of Kendall coefficient of concordance and Spearmen criterion showed consistency of expert opinions and comparability of the level of assessed risks criticality. The most critical risks include risks related with mistakes in provided data and created plan and also risk of provided data unreliability. A key way of identified risks elimination is automating of studied process. After development of automated planning system and implementation of all methods for risks elimination or minimization, risk of wrong data entry into the system was assessed by HRA method.

The paper presents the experimental results of studies of the thermal conductivity and electrical conductivity of composite materials based on dimethylsiloxane SKTN A and carbon black filler. The percolation and their similarity in the processes of heat transfer and electrical conductivity are analyzed. The correspondence of experimentally observed percolation threshold values to theoretical descriptions is discussed.

The article presents the results of studies of the physical, mechanical, thermal and electrical characteristics of composite materials based on polyurethane as a binder and mineral fillers from fine powders AlN, Al(OH)3, SiO2, CaSiO3 with a content of up to 70 wt.%. These composite materials are used to create modern sealants and dielectric coatings that meet special requirements for strength, elasticity, heat resistance, including those that do not support combustion (by using flame retardants). Dependences of tensile strength, coefficient of elasticity, modulus of elasticity under compression and hardness of samples, electrical resistivity and thermal conductivity on the mass content of the filler were determined. It was found that in terms of the combination of physical and mechanical characteristics, the compositions based on the applied polyurethane are more durable, elastic and resilient than compositions based on a silicone binder with the same fillers previously studied by the authors.