No abstract

Введение. Исходя из многофакторности патогенеза развития артериальной гипертензии (АГ), в настоящее время широко используют средства комбинированной антигипертензивной терапии. Поскольку в каждом конкретном случае преобладает один из нескольких механизмов повышения АД, комбинированная терапия АГ обеспечивает более выраженный гипотензивный эффект по сравнению с монотерапией [1, 2, 3, 4, 5].

The article presents the results of neurological examination of 95 patients with drug dependence. Neurological symptoms were evaluated comparatively in patients with non-injecting and injecting forms of dependence (n=17 and n=78, respectively). The obtained data of clinical neurological examination were compared with the indicators of magnetic resonance imaging of the brain and neurophysiological assessment of the state of peripheral nerves. A comprehensive analysis of the results of the study indicated that chronic intoxication with injecting drugs leads to the development of more pronounced and polymorphic neurological symptoms. It is also necessary to take into account the key role of intoxication in the formation of a cascade of reactions that change the functions of the nervous system.

Research of the last decade, which revealed the relationship of various socially significant diseases (Alzheimer’s disease, parkinsonism, multiple sclerosis, etc.) with the impact of heavy metals on the human body, stimulates modern science to create drugs that can quickly and safely remove these toxic substances from the body. The article presents a review of studies on the effectiveness of heavy metal adsorption by modern enterosorbents officially registered in the Russian Federation as drugs. The prospects of using non-starch polysaccharides, which are part of modern biologically active additives, in order to create new medicinal substances for the elimination of heavy metals that pose a threat to public health are indicated.