Relevance. Sexually transmitted infections (STIs) remain an urgent problem in modern society due to the high incidence of morbidity, the development of complications, including cancer, affecting the reproductive health of the population. The purpose of the study is to assess the incidence of sexually transmitted infections in the Republic of Tatarstan, including the incidence of certain nosoforms (syphilis, gonorrhea, trichomoniasis, chlamydial infection anogenital warts and urogenital herpes) in the period 2013-2017. Material and methods. A descriptive epidemiological study was conducted-a retrospective analysis of the incidence of STIs in the Republic of Tatarstan. We analyzed the long-term dynamics of the overall incidence of STIs, as well as for the nosoforms of STIs for the period from

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BACKGROUND: Since the beginning of the pandemic of a new coronavirus infection, preventive measures aimed at combating the spread of the pathogen, preventing the development of severe forms of infection and deaths have been improved. Despite the absence of a legally established generally accepted post-vaccination protective value of antibodies to coronavirus, the study of the presence of antibodies and the determination of their amount in the blood serum of the vaccinated population continues. AIM: The aim of the study is to present the results of the study of humoral immunity to SARS COV-2 in medical organizations. MATERIALS AND METHODS: The study involved employees of medical organizations of the State Autonomous Health Institution "Republican Clinical Dermatovenerologic Dispensary of the Ministry of Health of the Republic of Tatarstan named after Professor A.G. Ge" in Kazan and the State Autonomous Health Institution "City Polyclinic No. 3" in Naberezhnye Chelny in the number of 393 people who were vaccinated with the two-component vaccine GamCovidVac (Sputnik V), after which a sufficient amount of time has passed for the formation of an immune response: more than 21 days. The blood sera of 393 people (including 350 women) were examined for the determination of specific IgG to SARS-CoV-2 by enzyme immunoassay using the Vector-Best kit (Novosibirsk, Russia). Statistical analysis was carried out using the StatTech v. 2.8.8 (developer - Stattech LLC, Russia). RESULTS: The median of the age of the subjects was 47 years (Q1 - Q3:39-59). The mean antibody titer level was 570 BAU/ml (Q1 Q3:128-1150). A correlation analysis of the relationship between titer levels and age at the time of vaccination was performed, according to the results of which a weak direct relationship was established, and when assessing the dependence of antibody titer levels on the duration of vaccination after the second component at the time of checking the titers, there was no connection. CONCLUSIONS: The ongoing pandemic of a new coronavirus infection with the emergence of new forms of the disease caused by other strains of the virus, the improvement of prevention methods, requires constant monitoring of the epidemiological situation with the study of the effectiveness of vaccines, including at the cellular level.

Aims: To present the epidemiological characteristics of the incidence of microsporia in the population of the Republic of Tatarstan, including among residents of Nizhnekamsk district. Materials and methods: A retrospective analysis of the incidence of microsporia in the population was carried out according to official statistical forms for 2011-2021. The analysis of outpatient charts and medical histories of residents of Nizhnekamsk district with a diagnosis of microsporia, who applied to a dermatovenerologist in 2020-2022 and were hospitalized in a skin and venereological dispensary, journal of infectious diseases f. No. 060/y, was selectively carried out. The data were processed in Microsoft Excel (USA) and Startech (Russia). Results: In 2011-2021, there is a statistically significant trend towards a decrease in the incidence of microsporia in the Russian Federation, while in the Volga Federal District and the Republic of Tatarstan there is an increase, with residents of Tatarstan accounting for 66% of newly detected cases of microsporia in Russia and 59% in the Volga Federal District. High rates of microsporia incidence in the republic are registered among city residents (81.3%). During the analyzed period in Tatarstan, children aged 0-14 (77%) predominate among children with microsporia, mainly girls (42%), among adults persons aged 18-29 (9%) with a predominance of females in this group (7%). When analyzing outpatient records of patients-residents of the Nizhnekamsk district of the Republic of Tatarstan (n=919), the age distribution of children showed that the main subgroup with microsporia were children aged 7-14 years ‒ 519 people (51.4%). Every year, 53.9% of schoolchildren and 28.6% of preschool children get dermatophytes. The source of microsporia infection was stray and domestic cats 298 cases (29.5%). The main part of patients with microsporia 83.9% (298 people) were patients with localization of the process on smooth skin. In children, microsporia was represented by: smooth skin lesions in 744 cases (80.9%), scalp in 175 (19.1%). In adults: 83 cases of smooth skin lesions (97.8%), 8 of the scalp (2.2%). Conclusions: The problem of microsporia remains relevant due to its high prevalence, especially among children/ The continued growth of morbidity rates in Tatarstan is an indicator of the instability of the epidemiological situation, and indicates the need to improve measures to prevent their spread, including in cooperation with the veterinary service.

The purpose — is to assess the opinion of medical personnel about vaccination. Material and methods. Microsoft Excel 2010 and Openapi online calculator were used to analyze the results of questioning medical personnel about the role and necessity of immunoprophylaxis of infectious diseases. Results. A positive attitude to vaccination was recorded in 80% (95% CI 66,7–93,3%) of respondents. The majority of medical personnel — 87% (95% CI 81,3–92,7%) heard negative feedback about vaccinations from the population. Medical personnel are more likely to choose free of charge vaccinations — 82% (95% CI 75,5–88,5%), based on their availability, reliability and a high level of control. The majority of respondents — 96% (95% CI 92,7–99,3%) noted a high level of education on immunization issues. However, doctors are statistically significantly more likely to consider vaccination a necessary preventive measure than nursing staff (criterion χ2 = 19,35; df = 1; p = 0,00001090). Regarding the vaccine against the new coronavirus infection COVID-19, the majority — 60 people (43,5%) (95% CI 35,2–51,8%) of medical professionals have not yet decided whether they will be vaccinated or not. Conclusion. The study results demonstrated the proper level of immunization of medical personnel and their positive attitude to vaccination in general. However, frequent negative reviews of the population indicate the need for information work among the population about the purpose and importance of vaccination in the society.