The article presents the results of monitoring of senior medical students, including those with disabilities and / or with disabilities, which included testing and an oral survey aimed at determining their professional readiness. Modern approaches to training specialists for the field of practical health care, their professional mobility within the industry, the development of high-tech medicine, the need of society for a variety of specialists in the field of practical health care and the decline in the prestige and popularity of a number of medical specialties cause the problem of readiness of senior students of medical universities for professional activity. The relevance of this research is due to the following factors: increasing integration of medical education and practical health care, increasing their role in science and society, changing the structure and content of medical education; the existing need to study the process of forming the readiness of senior students of medical universities for professional activity; the need to identify new ways and means of forming the readiness of senior students of medical universities for professional activity.