There was performed the analysis of the primary disability of multiple sclerosis in a large industrial city of Ufa during the period of 2010-2016. There was noted the decline in levels of the disability from 0.23 in 2010 to 0,14 per 10,000 in 2016, the prevalence in the structure of disability in young and middle-aged, persons with the third disability group. During the first 5 years from the onset of the disease 36,8% of patients have signs of the permanent disability, after 10 years 62% of cases show signs of the permanent disability. The majority of the disability have secondary progressive and remission-progressive type of the disease.

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The analysis of the structure and dynamics of total disability due to multiple sclerosis in the city of Ufa from 2010 to 2016 years. 256(48,5%) patients including 72% out of them of working age have the persistent disability. The majority of persons with disabilities (57%) have secondary-progressive course of the disease. The average age of persons with disabilities due to multiple sclerosis accounted of 47.3 ± 11.6 years, the average score on the EDSS of persons with disabilities was 5.3 ± 1.3 points, the average duration of the disease before the appearance of signs of persistent disability accounts of 9.8 ± 8.2 years. Economic losses due to disability from multiple sclerosis in Ufa amounted to 3 543 493 849,15 RUB.