Several monolithic macroporous polymer sorbents (pore size 1-2 μm) based on alkyl meth acrylates and ethylene glycol dimethacrylate as a cross linking agent were prepared by free radical copolymerization in columns 3×150 mm. The influence of compositions of the reaction mixture and porogens and the nature of the alkyl radical in a mixture of monomers on the hydrodynamic and chromatographic characteristics of the monoliths was studied. The mono liths based on n butyl methacrylate have rigid macroporous morphology and excellent hydrody namic characteristics (flow rate up to 5 mL min -1 ). The efficiency of separation of a mixture of benzene and its derivatives in the version of reversed phase HPLC was shown to increase with an increase in the fraction of a lauryl methacrylate additive (LMA) in the reaction mixture. The maximum separation efficiency (number of theoretical plates (tp)) was 35 000 tp m -1 for the monolith based on n butyl methacrylate with 7% LMA in the reaction mixture.

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