The lecture sets out modern ideas about the etiology of viral hepatitis E, considering its species, physical and chemical properties. The questions of epidemiology are covered, namely, a characteristic of the zones of the spread of the virus, transmission routes, depending on the genotype of the virus, is given. Issues of the pathogenesis of the disease are also given taking into account new data on the virus genotypes. The acute and chronic forms of the course of the disease and extrahepatic manifestations of this infection are described. Their clinical picture, laboratory diagnostic methods, modern principles of therapy and prevention are given.

The lecture is devoted to non-specific prevention of coronavirus infection. Various measures are described to prevent the spread of COVID-19 to both the public and healthcare providers. The characteristic of various measures for the disinfection of medical and household waste is given. A detailed description of various personal protection methods with a description of the rules for their use is given. Attention is drawn to the rules for the use of personal protective equipment during a pandemic. Attention is drawn to common errors encountered when using personal protective equipment. The importance of their use in order to prevent the spread of infection outside medical institutions is emphasized.

The article presents the basic principles of antiviral therapy for hepatitis C. The main objectives and importance of antiviral therapy for hepatitis C are considered. The concept of a sustained virological response is given. The necessity of determining the causal relationship between infection with the hepatitis C virus and liver damage is substantiated. The article discusses the principles of antiviral therapy using interferon and interferon-free therapy with direct-acting antiviral drugs in both patients with acute and chronic hepatitis C.