High basal production of primary active oxygen forms was detected in the peripheral blood neutrophils of patients with renal cell cancer. In vitro stimulation of neutrophils led to more rapid release of superoxide radicals into extracellular space and to a reduction of cell capacity to more intense production of primary active oxygen forms.
Objective: Research purpose was to study phagocytic activity and a oxygen depended metabolism of blood neutrophils (NF) at patients with a renal cell carcinoma in dynamics -before operation and after surgical treatment. Methods: Patients with a locally invasive renal cell carcinoma (T 3 N 0 M 0 )were put under observation before surgical treatment (n =84) and in 10 days after a radical nephrectomy (n =54)
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