Combination intraarticular administration of Poviargol (0.5 mg/kg) and nicotinic acid (1.0 mg/kg) reduced symptoms of local and general inflammation in rats with adjuvant arthritis. We revealed a decrease in morphological signs of inflammatory degeneration of joint tissue and reduction of metabolic disorders.

Summary. Objective: to characterize the dental health of adolescents with arterial hypertension and to increase its level with a complex of therapeutic and prophylactic measures based on the results obtained. The study included 130 adolescents (65 – with arterial hypertension and 65 – control group) of 14.3 ± 2 years old. The level of systolic blood pressure in the main group was higher than that of the adolescents in the control group (126.6 ± 12.6 mm Hg vs 113.2 ± 7.4 mm Hg, p=0.00009), while the level of diastolic blood pressure was comparable. The data obtained suggest that adolescents with arterial hypertension are characterized by unsatisfactory oral hygiene indicators and a significantly higher incidence of major dental diseases: dental caries and periodontitis. It justifies the selection of adolescents with arterial hypertension in a group that is vulnerable both to the development of new and to the progression of existing diseases of the dental-maxillary system, which can significantly worsen cardiovascular health. Therefore, there is a need to develop a system of preventive actions built on the basis of an interdisciplinary approach with the active participation of somatic and dental specialists.Conflict of interest: The authors of this article confirmed the lack of conflict of interest and financial support, which should be reported.