The main factors of the working environment that harm a woman’s health in the course of work are considered to be physical exertion and functional overstrain, noise, chemical and biological factors, and microclimate. The most unfavorable sectors of the economy in the Republic of Bashkortostan are manufacturing, construction and the agricultural sector, where the largest number of jobs are registered that do not meet the hygienic standards for the above-mentioned production factors, which undoubtedly serves as the main cause of the development of occupational diseases among women. Material and methods.According to the medical records of the inpatient patient, the acts on the case of occupational disease and the registration form No. 30, the etiological causes and the structure of occupational morbidity by industry sectors of the Republic of Bashkortostan among women for 2016–2020 were studied. Results. Among the subjects of the Russian Federation, the Republic of Bashkortostan for the analyzed fiveyear period ranked 25–27th in terms of employment of women in jobs with harmful and (or) dangerous working conditions, and among the 14 regions of the Volga Federal District — 3–5 places. If in the period 2016–2019 among all the primary established occupational diseases from 32.4 to 43.0 % were women, then by 2020 more than half of all occupational diseases (54.7 %) were detected among women. Of the 114 cases of occupational diseases identified to 85 female workers, a third of them worked in health care (32.9 %), a slightly smaller part (30.6 %) — in mechanical engineering (manufacturing) and a fifth — in the agro-industrial complex (21.1 %). The leading place in the structure of occupational pathology of women was occupied by diseases associated with high physical overload and overstrain of individual organs and systems (54.2 %). The reason for the change in the structure of occupational diseases in the region in 2020 there was a new coronavirus infection-Covid-19 in medical workers, which brought diseases from the influence of a biological factor to the second position. Conclusion. The state of working conditions and occupational morbidity among women workers indicates the lack of an effective mechanism for protecting women’s labor and the need to develop effective legislative documents for the protection of their labor and health.

Introduction. One of the major petrochemical complexes of the Republic of Bashkortostan is Limited liability company (LLC) «Gazprom Neftekhim Salavat». The normal operation of industrial enterprises requires the use of large volumes of water. Its water supply, water disposal, waste disposal, reclamation of sludge reservoirs, equipment repair, cleaning of oil sludge reservoirs is provided by LLC «PromVodoKanal». The main technological personnel are wastewater treatment operators, process plant operators, pumping plant operators, chemical analysis laboratory assistants, commodity operators. Their work is associated with exposure to harmful and / or dangerous production factors. Objective. Search and substantiation of laboratory markers of early health disorders in workers of water supply facilities of petrochemical enterprises. Materials and methods. Hygienic and clinical laboratory studies were carried out among workers of the main occupations of the «PromVodoKanal» station who have contact with various harmful derivative factors. A complex of hematological and biochemical research methods was used in the work. Results. A comparative analysis of the frequency of occurrence of deviations of hematological parameters from the norm in all examined (occupational) groups was carried out. A laboratory study showed that hematological parameters are characterized by an increased content of hemoglobin, erythrocytes, and hematocrit. Changes in the mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC), and thrombocytes count, were detected in every fifth worker. Over the years of work, the share of workers with high levels of glucose and cholesterol increases markedly, the correlation of which reaches from 0.90 to 0.97. Limitations. The article has limitations on the scientific study of working conditions, as periodic medical examinations are carried out by occupational pathologists. Conclusions. Red blood values are specific markers of workers’ health problems and require special attention during periodic medical examinations.

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