The article presents results of analysis of the register of out-patients and in-patients with atrium fibrillation (n=1624) observed in 2009-2015. The retrospective data analysis and prospective observation of certain percentage of patients were applied to evaluate rate and conformity of implementation of various groups of anti-thrombotic medications in conditions of real practice of polyclinics and hospitals of Moscow. The results are compared with data of national studies of this issue during recent years.

Review of Russian and foreing clinical guidelines in aspect of digoxine use in chronic heart failure. Main clinical trials in this area are briefly discussed. Key questions of practical digoxine use at various categories of chronic heart failure patients are covered.