Aim. To determine the effectiveness of indirect antibiotics and lymphotropic therapy for the systemic inflammatory response syndrome correction in patients who underwent abdominal surgery.Methods. There were two groups with systemic inflammatory response syndrome in the postoperative period: 212 patients with various diseases of the abdominal cavity, who received conventional systemic complex therapy, and 146 patients whose complex treatment included antibiotics and lymphotropic therapy (administration of the cephalosporin antibiotics with lymphotropic mixture into the tibia subcutaneous tissue with the prior venous stasis creation). In both groups, patients with destructive forms of cholecystitis and appendicitis complicated by local or general peritonitis dominated. The dynamics of systemic inflammatory response syndrome clinical indicators, as well as laboratory parameters were assessed: the white blood cells count, leukocyte intoxication index, C-reactive protein and blood albumin. The data obtained on the 1st, 3rd and 5-6 days after surgery were analyzed.Results. In both groups clinical and laboratory symptoms positive dynamics was noted, which was more pronounced in the main group. In the control group leukocyte intoxication index increased on the third day and then decreased, but did not reach normal values on 10th day, while in the main group leukocyte intoxication index decreased already on the third day with its full normalization to 10th day. A faster normalization of white blood cell count, albumin level and C-reactive protein concentration decrease are also observed in the main group. Using indirect lymphotropic therapy was associated with reduction of postoperative complications and lethality rates.Conclusion. Lymphotropic therapy is an effective method of the systemic inflammatory response syndrome correction and can be recommended for the postoperative management of patients with abdominal surgery.

Aim. To evaluate the effectiveness of using ozonated solutions combined with decamethoxin solution in the treatment of purulent wounds.Methods. 101 patients with purulent wounds were under observation. In the treatment of all patients, the first stage was surgical debridement, which removes exudate and non-viable tissue. Also the conditions for wound drainage and good drainage of wound exudate were created, and then the treatment of wounds under a bandage was performed. In the main group (51 people) in addition to the basic treatment ozonated 0.9% sodium chloride solution with a concentration of ozone 8-10 μg/mL and 0.02% decamethoxin solution were used. The general condition of patients and the wound condition were evaluated over time.Results. The duration of fever and pain syndrome did not differ in the groups. A statistically significant difference between groups in the terms of symptoms disappearance and wounds healing was found, indicating the advantages of using the decamethoxin solution in combination with ozonated 0.9% sodium chloride solution in treatment of purulent wounds. The length of stay in hospital statistically significantly decreased compared to the control group. Positive dynamics was observed on the wounds cytology: starting from 3 days of treatment in the main group neutrophil count decreased, number of lymphocytes and polyblasts increased. With the increase in terms from the beginning of the treatment, there was even greater reduction in the number of neutrophils, the increase in the number of lymphocytes and the appearance of macrophages and fibroblasts.Conclusion. The study results demonstrated the benefits of using combination of ozonated solutions with decametoxine solution in the treatment of purulent wounds; method is available to any surgical wards and outpatient clinics.

Aim. To present the treatment results of patients with liver echinococcosis using abdominisation method to eliminate the fibrous capsule cavity.Methods. Method of fibrous capsule abdominisation was used in 73 patients with liver echinococcosis. Primary echinococcosis was diagnosed in 68 patients, relapse - in 5. An important condition for the surgery success is a thorough examination of the residual capsule to detect biliary fistulas and in case of their presense - a reliable suturing of the fistula with the subsequent control of their hermeticity and drainage. The fibrous capsule cavity and subphrenic space were drained using fascines drainage through which the fibrous capsule cavity was irrigated with ozonated sodium chloride solution and 0.02% dekasan solution.Results.. Postoperative complications occurred in 4 patients, and were presented with bile leakage, pleuritis and wound infection. There were no fatal cases. During the course of treatment biochemical tests results of patients who underwent fibrous capsule abdominisation, and patients in whom the fibrous capsule elimination was performed by capitonnage and intussusception were compared. The best results were found in patients with fibrous capsule abdominisation. Abdominisation method is reasonable for cysts of medium and large sizes (up to 15 cm in diameter), and in cases when the cavity elimination has a risk of blood vessels and bile ducts damage.Conclusion. Our research showed the possibility to perform fibrous capsule cavity abdominisation in liver echinococcosis, this method does not worsen liver functional state compared with capitonnage and intussusception.