The treatment of pulmonary valve disease is one of the urgent problems of modern cardiology and cardiac surgery. In most cases, pulmonary valve abnormalities are congenital. Synthetic conduits (homografts) and bioprosphetic valves are currently used in the surgical treatment of patients with the diseases mentioned above. Pulmonary valve surgical prosthetics allows normalizing the circulatory dynamics and condition of the patient, however, time-dependent degradation results in conduit and valve dysfunction. The abnormal circulatory dynamics caused by valve and conduit dysfunction is linked to exercise intolerance, arrhythmia, right ventricular failure, and sudden death. Starting in childhood, affected patients undergo repeated openheart surgeries to restore valve function and potentially reduce morbidity and mortality. Percutaneous transcatheter treatment of the pulmonary valve stenosis with the Melody® valve (Medtronic Inc.) has been performed in a large number of patients worldwide. Despite minimal invasiveness, this procedure restores pulmonary valve function and reduces repeated open-heart interventions. Recent clinical trials have shown excellent and durable results in terms of both restoring valve function and decreasing right ventricular outflow tract obstruction. In this article, we want to reflect the relevance of the Melody transcatheter valve and present our first experience of its usage.

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The relevance of the problem of prophylaxis and treatment of perioperative arrhythmias is due to the fact that a widening range of surgical interventions is performed, including elderly patients, burdened with concomitant cardiac pathology. The article reviews Russian and foreign clinical guidelines and handbooks for managing patients with bradyarrhythmias in non-cardiac surgery. Key in- formation about the physiology of electrical impulse in the myocardium, the formation of a normal ECG, as well as the main signs of cardiac rhythm pathology is given; “safe” and potentially dangerous bradyarrhythmias are indicated. The mechanism of development of intraoperative reflex bradycardia, which is a specific complication of some ophthalmic, maxillofacial and laparoscopic operations, is con- sidered. The review presents managing patients with certain types of bradyarrhythmias in the perioperative period: sinus bradycardia, sinus node weakness syndrome, conduction disorders. Separately the questions of implantable antiarrhythmic devices, anesthesia during arrhythmic operations are described. The analysis of recommendations on the choice of the method of anesthesia, monitoring, used drugs in patients with concomitant cardiac arrhythmias, the algorithm of emergency therapy in the perioperative period for potentially dangerous forms of bradyarrhythmia was conducted.

Objective. Estimate baseline coagulation profile values in patients scheduled for cardiosurgical intervention in age groups of pediatric population.Material and methods. The coagulation profile was analyzed in a complete selection of patients admitted to the intensive care department of Scientific Research Institute – Ochapovsky Regional Clinical Hospital #1 for the period from January to December 2018. The study includes 842 patients planned for cardiac surgery.Results. This study demonstrates the dependence of the basic parameters of the hemostasis system on age characteristics, mainly during the period of the first year of life. APPT values were similar in all age groups, whereas extended PV was recorded in patients less than one year.Conclusion. Evaluation of coagulation system parameters should be based on age-specific reference values. Understanding the concept of developing hemostasis is extremely important in conditions of optimal prevention, diagnosis and treatment of hemorrhagic and thrombotic conditions in the pediatric population.

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