Резюме. За последние десятилетия во многих странах мира все более острой становится проблема нарушений сна, причем это совпадает с ростом заболеваемости ожирением. Сложность изучения патогенетических связей между данными патологиями заключается в наличии множества факторов, влияющих как на развитие и прогрессирование ожирения, так и непосредственно на сон. Наиболее часто встречающиеся нарушения сна у пациентов с ожирением-синдром обструктивного апноэ сна и синдром инсомнии. В обзоре литературы представлены сведения о взаимосвязи нарушений сна с ожирением, где ключевая роль отводится изменению секреции гормонов, регулирующих аппетит и энергетический баланс.

No abstract

No abstract

No abstract

The aim of this study was to investigate the relationship between the dynamics of body weight and sleep disorders in the treatment of obesity.Materials and methods. The study included 200 obese patients: 83 men and 117 women.Results. Complaints about problems sleeping (snoring, hypersomnia, insomnia, etc.) were present in 78% of obese patients. 89 patients were under the observation of an endocrinologist for 7 ± 1 months, they were divided into three matched by age, sex and BMI groups: patients with obstructive sleep apnea syndrome (OSAS) (n = 42), the second – with the syndrome of insomnia (n = 19), the third (control group) – patients without sleep disorders (n = 24). After treatment of obesity the weight loss in patients with insomnia syndrome was -2.5 [-4; 0]kg, in patients with OSAS -7 [-18; -2] kg, in patients without sleep disorders -6.5 [-12; -2.25] kg. Clinically significant weight reduction was reached in 25 (59.5%) patients with OSAS; 3 (16%) – with insomnia syndrome; 15 (62.5%) – without sleep disorders.Conclusion. Thus, the insomnia syndrome essentially influences the obesity treatment results – most of patients with this sleep disorder (81.2%) do not achieve clinically significant weight loss. The presence and severity of breathing disorders during sleep do not prevent weight loss. However, with the regular use of CPAP-therapy in patients with OSAS has a tendency of greater reduction of body weight.