Авторское резюмеЦелью исследования являются проведение тестирования гаплогруппы Y-ДНК славянского раннесредневекового захоронения могильника в окрестностях поселка Загорянский (у д. Городище, могильник Болшево-1) на р. Клязьме, поиск его возможных аналогов в других образцах средневековой ДНК и историко-археологическая, антропологическая и генетическая интерпретация результата. Данные говорят о принадлежности индивидуума к гаплогруппе E1b1b, что свидетельствует об участии дунайского компонента в этногенезе данной группы кривичей, пришедшей с Верхней Волги и новгородско-смоленского пограничья.Ключевые слова: генофонд, популяционная генетика, палео-ДНК, контаминация, SNP-и STR-маркеры Y-хромосомы, мт-ДНК, гаплогруппы, секвенирование.
AbstractThe aim of the study was to test the Y-DNA haplogroup of the Slavic early medieval burial of the ground Bolshevo-1 (near Zagoryansky settlement) on the Klyazma river, to consider its possible analogues in other samples of medieval Slavic DNA and to give a historical, archaeological, anthropological, and genetic interpretation of the result. The data show that the individual belongs to the haplogroup E1b1b, which indicates the participation of the Danube component in the ethnogenesis of this group of the Krivichs, which came from the Upper Volga and the Novgorod-Smolensk border.
The study aims at determining Y-DNA and mtDNA haplogroups of two early medieval Slavic burials at Bolshevo-1 burial ground (near Zagoryansky settlement) on the Klyazma River to consider their possible analogs in other samples of medieval Slavic DNA and to give a historical, archaeological and anthropological interpretation of the result. The comparison of the skulls from Bolshevo-1 with the craniological Slavic series has shown their proximity to the Serbian and West Slavic series. The belonging of Individuals 5666 and 5672 to Y-DNA haplogroups E1b1b and J2a1 suggests the Danube component in the ethnogenesis of this group of the Krivichi tribe, which came from the Upper Volga and the Novgorod-Smolensk border. The mitochondrial haplogroup of Individual 5666 H1e1b allows considering the Baltic branch of the ethnogenesis of this group.
Analysis of pregnancy course, labor and early neonatal period at 294 women and their new-born children has been made for the estimation of the efficacy of different antibacterial therapy variants of urogenital clamidiosis during the second half of pregnancy period. The danger of abortion and chronic intrauterine fetal hypoxia are most often gestational process complications revealed against chronic urogenital clamidiosis. The use of sumamed is course dose of 3 g is an optimum pharmacotherapeutic regimen during the second half of pregnancy period.
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