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Abstract-ZnO nano-rods grown by gaseous-disperse synthesis (GDS) are confirmed by XRD analysis to have the wurtzite crystal structure. The obtained crystallites, as found from SEM studies, are 57±9 nm in diameter and 470±30 nm long on the average. Two emission bands of photoluminescence from ZnO nano-rods observed at room temperature are centered at 376 nm and 520 nm. A bio-sensitive layer is prepared by immobilization of Anti-Salmonella antibodies (Ab) from liquid solutions on the ZnO surface. Immobilization of the bio-sensitive layer onto ZnO nano-rods is found to increase the intensity of PL. After further reaction with Salmonella antigens (Ag) the PL intensity is found to decrease proportional to antigen concentrations in the range of 1000 -1000000 cell/ml. The possible mechanism of biosensor response is suggested and discussed.

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