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The aim. Discussion of a clinical case of Crohn’s disease in a patient with chronic kidney disease on program hemodialysis.Materials and methods: the study analyzed the medical history of a patient diagnosed with Crohn’s disease with severe comorbid pathology.Results. The provoking factors for the development of Crohn’s disease in a patient with ciliopathy (cystic disease of the kidneys, liver, lungs), ankylosing spondylitis, secondary polyosteoarthrosis, undergoing hemodialysis are discussed.

Crohn’s disease sickness rate is 0.3–0.2 per 100000 persons, its prevalence is 322 per 100000 persons; Up to 60–70 % of patients with Crohn’s disease undergo this or that type of surgical intervention – from opening of paraproctitis to extensive intestinal resections. Uninterrupted course of disease and probability of severe relapses induce application of long postoperative drug therapy to avoid repeated operations. Repeated resections of the bowel in Crohn’s disease are dangerous from the position of the development of short bowel syndrome, severe digestive disorders. Surgical treatment in Crohn’s disease is aimed at prevention of complications and improvement of patients’ quality of life, if drug therapy is useless.

Nowadays there are certain difficulties in the early diagnosis of ulcerative colitis, proceeding with minimal intestinal symptoms. The etiology of the disease remains unclear to this day; there is no exact information about the prevalence of the disease due to the large number of latent forms and the low number of patients seeking medical help. This article presents the results of a retrospective analysis of the incidence of ulcerative colitis in the coloproctology department of the First Republic Clinical Hospital of Izhevsk. The study was conducted to assess the frequency of occurrence and determine the internal picture of ulcerative colitis. To achieve this goal, we selected 34 patients with ulcerative colitis. A statistical study was conducted on the following criteria: gender composition, age groups, forms of the disease, localization, complications, and main complaints. The length of hospital stay often was not more than 20 days. The literature on this pathology was also studied and presented in the form of a theoretical basis, which consisted of the determination and etiology of inflammatory bowel diseases. Due to the unknown etiology, insufficiently studied pathogenesis, difficult differential diagnosis with other intestinal diseases and insufficiently perfect treatment methods, there are a large number of unresolved problems in the field of ulcerative colitis. That is why, in this article we tried to reveal the problem of the features of the course and complex therapy of that disease in clinical practice.