The research work was carried out in the period from 2014 to 2018 in the city of Tyumen. In this period 3.237 cats of different breeds and ages were examined. The investigated reproductive disorders were found in 389 cats. It was established that these disorders are widespread in Tyumen and their percentage ranges from 12.02 to ± 0.195Purulent endometritis was most often observed in the following breeds: Mestizo -32.89% of cases, Scottish fold -25.00%, British shorthair -14.47%, Abyssinian -7.89%. Cystic ovarian formations were recorded in Mestizos -46.56%, British short-haired -21.37%, Scottish folds -18.32%, Sphynxes -7.63%. Tumors of mammary glands were found in cats of such breeds as Mestizo -40.00%, Sphinx -23.63%, Persian -14.54%, Siamese -14.50%, Abyssinian -7.27%. The predisposition of cats to purulent endometritis has increased in the following age groups: 11.84% from 4 to 5 years old, 11.84% from 5 to 6 years old, and 10.52% from 7 to 8 years old. 11.45% of cats from 2 to 3 years old had predisposition to the ovarian cysts: 10.68% of cats were at the age ranging from 3 to 4 years old; 11.45% were from 4 to 5 years old; 11.45% were cats from 5 to 6 years and 12.21% from 6 to 7 years old. Tumors of mammary glands were registered more often in the age groups from 8 to 9 years old and amounted to 12.72%; from 9 to 10 years old this number comprised 12.72%; and over 10 years old it was 18.18%. To treat diseases or disorders of the reproductive system organs of cats, the gestagenic drugs produced either in Russia or abroad are used. In the Russian pharmaceutical market there are 33 gestagenic drugs. The share of domestic producers is 91%, which is equal to 92 items and the share of foreign producers is 9%, which is 9 items.

The paper presents the results of therapeutic efficiency of Komfortis, Foresto and Fitoelita medical agents used during flea infestation among domestic cats. For the study, the animals were divided into three groups 10 animals each. Clinical, hematologic and special research methods were conducted during the study. Blood sampling included three stages: before insecticides treatment, intermediate interval of 15 days, and the final stage. It is found that Komfortis and Foresto have 100% therapeutic efficacy at all stages of flea development and possess a long-lasting action during flea infestation. The morphological blood analysis showed that the proposed medical agents have no toxic or side effects.

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Introduction. Parasitic diseases are one of the main problems of horse breeding, in particular, helminthic infestations. The helminths are able to induce mechanical, toxic, inoculation effect. Moreover they absorb the nutrients necessary for the horse body. Thereby the helminths inflict significant harm on the horse population, not only due to animals deaths, but also due to weakening the protective functions of the body as well as working capability, sports and breeding qualities of horses. The aim of the present work is to study the epizootological aspects of helminthiases in horses at the territory of Tyumen region.Materials and methods. The study was carried out taking into account the horses keeping and care practices in twenty-two administrative districts of the region, located in the subzones of the northern and southern forest-and-steppe and subtaiga areas. To determine the infestation extensity (IE), the parasitological research methods of Kotelnikov-Khrenov, Fülleborn’s, Darling's modification method and the method of studying the scrapings of the perianal folds of the horse were applied. Results. During the research it has been found that the infestation extensity in horses infested with helminths in the Tyumen region averages to 27.9 ± 1.43 %. Whereas, the maximum helminthic infestation was found in horses in the subzone of the northern forest-and-steppe area IE 38.7 ± 1.97 % and the minimum in the subzone of the southern forest-and-steppe area IE 22.5 ± 1.16 %. It was found that in the conditions of year-round keeping in the stables with regular walking, the intestinal helminths parasitised in horses with the following infestation extensity (IE): Parascaris equorum 70.1 ± 2.53 %, suborder Strongylata 48.3 ± 1.97 %, Oxyuris equi 36.1 ± 1.63 %, the representative of Strongyloides westeri 20.9 ± 1.19 %. In the conditions of herd farming, the maximum infestation extensity in horses was observed for the helminths of suborder Strongylata with IE 74.0 ± 2.31 %, also spotted were parasites Parascaris equorum with IE of 41.2 ± 1.67 %, Oxyuris equi with IE — of 13.2 ± 0.87 % and the minimum infestation extensity was recorded for the parasites Strongyloides westeri with IE of 6.5 ± 0.21 %. In horses in the conditions of improved herd farming, the maximum infestation extensity was observed for the helminths of suborder Strongylata with IE of 79.4 ± 2.52 % and the minimum was for Strongyloides westeri with IE of 0.8 ± %. When studying the distribution of infestation in relation to the keeping and care practices, the data was obtained confirming that under practices of keeping in stables the helminths Parascaris equorum prevail with IE of 70.1 ± 2.53 % and under practices of herd and improved-herd farming the helminths of the suborder Strongylata with IE of 74.0 ± 2.31 % and IE 79.4 ± 2.52 %, respectively.Discussion and conclusions. Thus, in the result of studying the epizootic aspects of helminthiases in horses, it was found that helminthic infestation is recorded in various climatic zones throughout the whole territory of Tyumen region.

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