cial [1]. One of the possible causes of digestive tract diseases in children is the failure in the constantly growing body of regulatory systems and, above all, the autonomic nervous system [2]. Violations of vegetative homeostasis, leading to the disruption of the functions of organs and systems, contribute to a change in the level of metabolism and energy in the body and are an important pathogenetic link of many chronic diseases, including gastrointestinal ones [3]. It is assumed that the identification of features of the functioning of the autonomic nervous system and heart rate parameters will allow timely not only to diagnose, but also to correct their deviations [4].The purpose of this study was to explore the features of changes in cardiac rhythm and conductivity, identified on an electrocardiogram (ECG), in children with chronic gastroduodenal pathology. Materials and methods:The main group (I) consisted of 41 children aged 4 to 10 years (mean age 8,2) with chronic pathology of the gastroduodenal zone. Gender distribution was as follows: 18 boys (43,9%) and 23 girls -(56,1%). The control group (II) was 45 conditionally healthy children (without pathology of the gastrointestinal tract; from them -18 girls (40%) and 27 boys (60%), the average age -8,6 years, groups were comparable by age and gender. The diagnosis was established on the basis of complaints, anamnesis of the disease, general clinical examination, data of fibroadastroduodenoscopy, ultrasound examination of the abdominal cavity organs, tests for the presence of Helicobacter pylori.Results and discussion: The duration of the disease in the main group was as follows: 7 gastroduodenal pathology (17,1%), duration of the disease 1 year -14 people (34,1%), duration of the disease over 1 year -20 people (48,8%); the average duration of the disease in children was 2,2 years. Diseases of the stomach and duodenum (gastritis, gastroduodenitis) predominated in the study group -25 children (60,9%), from them -61,5% was diagnosed erythematous gastritis, in 7% children -gastroesophageal reflux; diseases of the gallbladder and biliary tract (dysfunction of the biliary tract) -3 patients (7,3%); pancreas diseases (manifestations of dispensiveness, pancreatopathy) -13 children (31,7%). 39% of children in first group had concomitant pathology: weight loss in 12,5%. 1/3 children form this group had concomitant pathology: weight deficit was in 12,5%, cardiac pathology -in 37,5%, orthopedic pathology -in 18,7% and 14% of children had endocrine and neurological diseases. According to the results of ultrasound in the main group, changes in the pancreas (structural changes, densification of the Virsung duct) were found in 41,2% patients, changes in the liver (reactive changes in the liver parenchyma, compaction of the periportal structures) were detected in 32,3% and changes in the gallbladder (deformation, inflection) -in 26,5% children.Having studied ECG data in the main group of changes, 95,1% of children were registered, which is significantly more likely than in...

At present time chronic obstructive pulmonary disease (COPD) is considered to be an airway disease with respiratory and systemic manifestations. Cardiovascular diseases have the largest influence on COPD severity among numerous coexisting diseases. These diseases are united together with such pathogenic factors as a sedentary lifestyle, disorder of lipid metabolism and hemostasis, endothelial dysfunction. Tissue hypoxia, oxidative stress, endothelial dysfunction, activation of neurohumoral systems, disorder of water-electrolyte metabolism, and also chronic systemic inflammation are the basic pathogenetic mechanisms of development of the coexisting cardiac pathology of patients with COPD. At the same time the regularities of changing of the clinical picture, peculiarities of a disease course, and also outcomes of COPD in case of comorbidity are still insufficiently studied. Today the main attention is focused on the introduction of noninvasive methods of diagnose of vessels’ elastic properties into clinical practice. Stiffness (rigidity) of the arterial wall studied through the use of the volume sphygmography method is considered to be one of the informative markers of cardiovascular morbidity and mortality. Pulse wave velocity depends on the stiffness of the vessel wall: the higher the vessel’s stiffness is, the thicker the vessel’s wall is and the smaller its diameter is, then the faster the pulse wave velocity is. An early disease detection of changings of arterial stiffness and metabolic disorders has an important clinic and prognostic value and makes it possible to coordinate therapy timely with the combined cardiopulmonary pathology and avert negative consequences of hemodynamic complications.

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