ACTH-ectopic syndrome in the patient with the primary site localized in the pancreas. A rare clinical case of ACTH-ectopic syndrome in the patient with the primary site localized in the pancreas is described.

At the moment, lactate-acidosis coma in patients with diabetes mellitus is considered a rare and extremely urgent condition that occurs in patients with concomitant diseases as well as when taking the most widely used sugar reducing drug – metformin. This article describes a case of lactate-acidosis coma with a fatal outcome, which occurred against the background of taking metformin and alcohol abuse, in a woman with type 2 dia-betes mellitus aged 48 years.