У доповіді розглянуто різні гіпотези щодо причин виникнення і розвитку хвороби Альцгеймера, проаналізовано сучасний стан і перспективи розроблення новітніх методів ранньої діагностики, створення нових препаратів для ефективного лікування цього нейродегенеративного захворювання. Наведено найважливіші результати, отримані вченими НАН України, щодо вивчення низки фундаментальних питань патогенезу ушкоджень мозку при хворобі Альцгеймера, що сприяло появі нових підходів до лікування цього захворювання.

The article deals with the main causes of chronic pelvic pain syndrome (CPPS), some of its pathogenetic mechanisms are depicted. It is noted that at the present time, CPPS, despite its considerable prevalence, remains poorly understood by a disease that is difficult to treat, the adequacy of which is possible only under the strict topical and nosological diagnostics. To date, there are no clearly identifiable etiological factors in the development of CPPS, and existing contradictory data regarding diagnostic criteria significantly reduce the possibility of a clear diagnosis. In addition, there is still no single approach to choosing the best treatment methods for CPPS, and the assessment of a large number of existing treatments for this disease is difficult due to the lack of a standardized system for evaluating the results of treatment. These circumstances, together with the steady course of the disease, lead to the formation of neurotic conditions, which emphasizes not only the purely medical but also the social significance of the problem of increasing the effectiveness of diagnosis and treatment of CPPS in boys at the present stage. The algorithm of diagnostics and treatment of CPPS is proposed, which is based on an individual and comprehensive examination of patients by multidisciplinary interaction with specialists of other specialties related to a specific case that allows choosing pathogenetically grounded treatment tactics