Improvement of the quality of working environment by creating safe working conditions, identification and classification of risks are the basic principles for the prevention of occupational and work-related diseases in workers during production and use of artificial mineral fibers. The most important stage of prevention is therapeutic and preventive measures, including prevention of occupational skin neoplasms in the production of continuous glass fiber, prevention of dusty lung diseases when using mineral wool, vibration- and noise-induced diseases, organization of therapeutic and preventive nutrition.

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Background. Periodontitis is a complex, multifactorial inflammatory disease. The prevalence in the adult population is 80-98%. The onset of the disease and the progression of the inflammatory process is associated with the colonization of the subgingival tooth surface with parodontopathogenic microorganisms. Objectives. The purpose is to study the prevalence of five oral microbes in subgingival plaque samples: Aggregatibacter actinomycetemcomitans (Aa), Porphyromonas gingivalis (Pg), Tannerella forsythia (Tf), Treponema denticola (Td), Prevotella intermedia (Pi) in oil and gas industry employees with chronic periodontitis and identify the presence connection between the clinical manifestations of periodontitis and the microbial profile of periodontal pockets. Methods. The study of periodontal microbiota was carried out in 32 workers in oil and gas industry employees with chronic periodontitis and in 32 patients with chronic periodontitis diagnosed not working in this field. Genomic DNA was extracted and 5 bacterial species were detected using the polymerase chain reaction. Results. Oil and gas industry employees with chronic periodontitis have their own flow peculiarities associated with the systematic influence of production factors. The most prevalent microorganism is Pg (77%), the presence of which is significantly associated with an increase in the depth of the periodontal pocket (PPD), clinical attachment loss (CAL), and an increase in the bleeding on probing (BOP). The pathogenic effect was manifested in the presence of the following microorganisms - the formation of the periodontal pocket in combination of Tf and Td, Tf and Pi, CAL level - Tf and Td, increased BOP index - Pg and Tf. Conclusions. As a result of the study, a connection was established between the red and orange complex bacteria with the clinical signs of chronic periodontitis. There was no significant association between age, smoking and the clinic of chronic periodontitis. Significant impact on the development of inflammatory periodontal diseases in oil and gas industry employees have harmful production factors.

Introduction. The high prevalence of circulatory diseases among workers exposed to hazardous occupational factors is an important medical and social problem. Material and methods. The study of working conditions and the state of the cardiovascular system in petrochemical workers has been carried out by using hygienic, clinical, laboratory and statistical research methods. Occupational and non-occupational factors of cardiovascular risks for workers have been studied. Results. As a result of complex clinical and hygienic studies, the contribution of occupational, non-occupational, and psycho-emotional factors to the development and progression of cardiovascular diseases in chemical workers has been established. The level of cardiovascular risk has been shown to be determined by the spectrum and intensity of the impact of occupational stress factors, the age and work-experience-related characteristics of workers Conclusion. The impact of occupational, non-occupational, psychosocial risk factors on the state of the cardiovascular system has been identified. The development and implementation of the multiple factor prevention system are imperative.