Relevance. Тhe quality of dental care is greatly influenced by the biocompatibility of the materials used. This problem is particularly acute in patients with a high level of sensitization, such as allergic rhinitis. Currently, the CAST-test is used to diagnose allergies and sensitization of the body. The method has 100% specificity and significantly complements the definition of IgE antibodies.Purpose. To determine the individual tolerance of dental materials in patients with allergic rhinitis.Materials and methods. 47 patients with allergic rhinitis were examined. All patients were sent to determine the test of spontaneous activation of peripheral blood basophils on dental materials: cobalt-chromium alloy; zirconium dioxide; glass ionomer cement; composite material; plastic for the basis of the prosthesis (non-monomer).Results. The Average values of the activation coefficient of blood basophils in patients with nasal breathing disorders were revealed for a kobolto-chrome alloy – 1.29 ± 0.02, for zirconium dioxide – 1.04 ± 0.02, for glass ionomer cement – 1.11 ± 0.04, for composite dental light – curing material – 1.24 ± 0.03, for plastic for prostheses (non-monomer) – 1.19 ± 0.02.Conclusion. The study shows the need for special attention to the planning of dental treatment in patients with nasal breathing difficulties, especially with allergic rhinitis. The frequency of detection of the coefficient of spontaneous activation of basophils test showed a 100% positive result for composite light-curing material and non-motionless plastic, in 91.5% of cases-for a cobolto chrome alloy. 100% negative result for zirconium diaxide and 82.9% of cases for glass ionomer cement.