In the short overview presents the trends and practice of folk medicine development in the Republic of Tyva, scientific directions in this field, and identifies the possibilities of integrating folk treatment methods into the health care system of the republic.
The purpose of the research: morphofunctional estimation of the gastroprotective activity of the dry extract from the roots and rhizomes of Ferulopsis hystrix in neurogenic ulcer.Materials and methods: The studies were carried out on white Wistar rats. The neurogenic ulcer was simulated by 24-hour immobilization of the animals. The gastroprotective effect of Ferulopsis hystrix was estimated taking into account the Pauls’ index which was calculated for bleedings, erosions and strip-like ulcers as well as taking into account the morphometric indices (the depth of erosions) of the stomach mucosa. The intensity of lipid free radical oxidation processes was estimated by malonic dialdehyde content (MDA); the state of the antioxidant system was estimated by the activity of catalase, superoxide dismutase and the reduced glutathione content.Results. The Ferulopsis hystrix extract in the doses of 100 and 150 mg/kg reduces the depth of erosions by 43% and 80% respectively, thus promoting the diminishment of destructive processes in the stomach mucosa against the background of neurogenic ulcer. The Ferulopsis hystrix extract in the given doses decreased the MDA content by 37% on average; the catalase activity was twofold increased; the reduced glutathione increases 2.6 times and SOD activity — 3.8 and 2.8 times respectively.Conclusion. Ferulopsis hystrix has the gastroprotective effect in neurogenic ulcer.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.