First, electromagnetic radiation of terahertz range at molecular spectrum frequencies of nitride oxide (from 150.176 to 150.664 GHz) is used in clinical practice for 30 patients with stenocardia and arterial hypertension. Antianginal, hypotensive, and hypocoagulative action of terahertz therapy is exposed. IntroductionSome years ago, for the first time, a group of Saratov's scientists suggested to use electromagnetic oscillations of terahertz range at frequencies that correspond to molecular spectra of the most significant cell's metabolites (NO, CO, 02, CO2, OH and others) for radiation of comlex biological objects [1]. This concept started a new scientific trend in the field of interaction between millimeter waves and living organisms that was called as terahertz therapy (THz-therapy). Now, the application of electromagnetic radiation at the molecular spectrum frequencies of radiation and absorption of nitride oxide (from 150.176 to 150.664 GHz) is a problem of the greatest interest. Nitride oxide is known to be not only a universal regulator of physiological and metabolic processes as in a separate cell and in an organism as a whole, but it also realizes intercellular interactions, functioning as a signal molecule practically in all organs and tissues of human and animals [2]. Investigations of electromagnetic radiation effects at molecular spectrum frequencies of NO (NO-THz-therapy) is essentially actual for cardiologists, because nitride oxide, possessing the properties of powerful neurotransmitter [3], inhibit the thrombocyte aggregation [4,5], participates in a blood vessel tonus regulation and now is considered as powerful antihypertensive factor [4,5]. In 2004, after investigating an influence of electromagnetic radiations at NO-molecular spectrum frequencies on healthy volunteers [6], at the first time, researches on studying the influence of NO-THz-therapy on the patients with cardioproblems were initiated. A purpose of the present paper is to estimate the efficiency and safety of terahertz electromagnetic radiation at the nitride oxide molecular spectrum frequencies (NO-THz-therapy) applied to patients with non-stable stenocardia, including the patients with accompanying arterial hypertension.
The results of clinical trials have proved that elevated heart rate (> 80-85 beats/min) at rest is directly related to the risk of arterial hypertension and atherosclerosis development, and it is a powerful predictor of cardiovascular morbidity and mortality. Epidemiological studies have shown that these relationships are independent of other risk factors of atherosclerosis and are present in asymptomatic individuals as well as in patients with cardiovascular diseases. The results of experimental and clinical studies suggest that hemodynamic changes due to elevated heart rate have a direct influence on the arterial wall, favouring the development of atherosclerotic lesions. Moreover, heart rate is directly related to the development of cardiovascular events associated with atherosclerotic plaque disruption. Based on these data we believe that heart rate should be listed among major risk factors for ischemic heart disease
There had been studied the effect of THz therapy of nitrogen oxide (NO) waves in effort angina at 36 middle-aged patients and at 20 patients of a certain age. Antianginal effect in the both groups did not differ. At the middle-aged patients (46-59 years) there had been revealed an increase of anticoagulant blood potency, at the elderly patients (60-74 years) -a decrease of natural procoagulant activity.
The aim of the study was to assess the role of the main branches of the polyenzyme system of erythrocyte glycolysis in the development of their energy-synthesizing insufficiency in the acute period of myocardial infarction.
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