Low-temperature plasma is a partially ionized gas obtained at atmospheric pressure and having a macroscopic temperature close to the ambient temperature. The composition of the torch of low-temperature plasma includes charged particles, neutral active particles, including free radicals and particles in metastable states, as well as ultraviolet radiation. The biological effects of plasma are associated with the synergistic effect of the listed factors, each of which has a subliminal concentration that does not cause changes in the biological object. Intensive research on the use of low-temperature plasma in medicine began about 10 years ago, although some pioneering work appeared much earlier, mainly in Russia. Since the mid-2000s. in the world began to actively develop sources of gas plasma, in which the temperature of the plasma torch is reduced to the temperature of the human body. The use of such structures makes it possible to subject the treated surface to direct plasma action and to use the entire spectrum of active plasma components, including photons, electrons, ions, free radicals, and molecules in an excited state. Low-temperature plasma has a number of fundamental advantages, which include high non-specific bactericidal activity, low probability of occurrence of stable forms, the absence of ionizing radiation and highly toxic substances. The described advantages together with a comfortable temperature, relative simplicity and low cost methods, the lack of specific requirements for the treated surface make low-temperature plasma a promising method for the treatment of various pathological conditions.

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We conducted an objective and instrumental examination in 79 patients with radical mastectomy in the early postoperative period (2–4days), patients of the 1st group n=23 underwent 10procedures of postoperative suture fluctuation; patients of the 2nd group n=28 underwent 10procedures of fluctuating currents according to the extended technique; and patients of the 3rd group n=28 in addition to the extended technique underwent fluoridation of the forearm muscles by the same parameters. It has been proved that patients have reduced postoperative swelling, reduced pain, reduced the number of postoperative complications in the wound (inflammation, infectious processes, pain, suture divergence), shortened lymphorrhea. There is an increase in the amount and quality of movements, reduced sensitivity disorders in the upper limbs. Thus, the inclusion in the program of medical rehabilitation of various methods of appointment of fluctuating currents in the early postoperative period is appropriate and helps to reduce the time of recovery.

Background.Plasma medicine is a new direction in science at the intersection of plasma physics and chemistry with biology and medicine low-temperature plasma (LTP) has a number of fundamental advantages, which include high non-specific bactericidal activity, low probability of the appearance of stable forms, the absence of ionizing radiation and highly toxic substances. In addition, LTP stimulates healing of infected wounds at the early stages of exposure, which makes LTP a promising method of treating various pathological conditions. Clinical case description.Low-temperature argon plasma treatment was performed for a patient with a diagnosis of: cancer of the right breast cancer T2N1M0, IIB stage. Condition after non-adjuvant PCT and radical resection of the right breast. Complication: Abscess in the area of the postoperative scar. After the 3rd treatment with plasma flow, the wound was sutured and while continuing treatment with low-temperature argon plasma, the patient began radiation therapy of the right breast and regional lymph flow zones in the mode of classical dose fractionation. During the follow-up period, the patient showed positive dynamics in the area of the postoperative scar, which did not lead to a long period of rehabilitation in the postoperative period and radiation therapy was started in a timely manner. Conclusion.Thus, the use of this technique in clinical practice has proven that the period of rehabilitation in the postoperative period is shortened for continuous comprehensive treatment of severe cancer patients with breast cancer.