The review of domestic and foreign literature devoted to epidemiological studies of myasthenia gravis has been reviewed. The article presents data on the prevalence and incidence of myasthenia gravis in several regions of Russia and abroad. The prevalence of myasthenia gravis in the world varies, according to different authors, in a very wide range – from 2.17 to 32.0 per 100 thousand people. There are few epidemiological studies of myasthenia gravis in large cities and regions of Russia. Meanwhile, studies of the prevalence and incidence of myasthenia gravis are a necessary stage in the work to increase the effectiveness of diagnosis and treatment of this pathology, to determine the need for specialized types of medical care. The results of these studies can be used to optimize the management of myasthenia gravis patients.
We considered the views of researchers presented in the modern literature on both the problem as a whole and discussion questions regarding the causes of development, preventive measures, and methods of treating percutaneous endoscopic gastrostomy complications, such as clogging of the gastrostomy tube, peristomal wound infections, necrotic fasciitis, pneumoperitoneum, buried bumper syndrome, growth of granulations in the gastrostomy zone, postoperative bleeding and intraparietal hematoma of the gastric wall, traumatic dislocation of the gastrostomy tube, peritonitis after percutaneous endoscopic gastrostomy, peristomal leakage, сolonic fistula, liver injury and abdominal wall metastasis at the percutaneous endoscopic gastrostomy site.
Как можно улучшить информационность неврологического статуса (коморбидное левшество) Резюме. Анализируются 200 пациентов с положительными тестами на скрытое левшество и исследованием когнитивных функций с применением авторского скринингового теста. Возраст больных -от 30 до 65 лет (в среднем 41,0 ± 5,3 года), из них мужчин -116 (58,0 %), женщин -84 (42,0 %). При использовании стандартного исследования неврологического статуса у них были установлены следующие неврологические коморбидные диагнозы: ишемический мозговой инсульт -у 22 больных (11,0 %), дискогенно-венозная люмбосакральная радикуломиелоишемия -у 74 (37,0 %), рассеянный склероз -у 16 (8,0 %), вегетососудистая дистония с гипоталамическими пароксизмами -у 74 (37,0 %), паркинсонизм -у 14 (7,0 %). Исследование тестов на скрытое левшество и состояние когнитивных функций в дополнение к стандартному изучению неврологического статуса значительно расширяет круг диагностических возможностей. Терапевтические и нейрореабилитационные мероприятия должны проводиться с учетом клинических симптомов и признаков всех коморбидных патологий и соблюдением правил хорошей клинической практики.
Chronic inflammatory demyelinating polyneuropathy (CIDP) is a heterogeneous immune-mediated peripheral neuropathy with progressive or relapse-remitting course. Incidence of CIDP ranged between 1 and 8.9/100 000. Recently, most frequent therapies for CIDP treatment was glucocorticosteroids, intravenous immunoglobulin and plasma exchange. In cases of ineffectiveness or lack of effectiveness, cytostatics, monoclonal antibodies and others could be used for CIDP treatment. In the article, authors presented an update data on the use of main methods for CIDP therapy, their mechanisms of action, indication for their use and advantages and disadvantages of each of them.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.