Email: timoshinova89@yandex.ruAbstract. While formulating a mathematical model of the flow and interaction between oxygen-methane fuel combustion products with tangentially swirled ballast water injected in the end of the combustion chamber in CAE product Fluent, which integrated into the ANSYS Workbench platform, the problem of structural-parametric synthesis is solved for structure optimization of the model. Equations are selected from the catalogue of Fluent physical models. Also optimization helps to find "regime" model parameters that determine the specific implementation of the model inside the synthesized structure. As a result, such solutions which were developed during creation of a numerical algorithm, as the choice of a turbulence model and the state equation, the methods for determining the thermodynamic thermophysical characteristics of combustion products, the choice of the radiation model, the choice of the resistance law for drops, the choice of the expression which allows to evaluate swirling flows lateral force, determination of the turbulent dispersion strength, choice of the mass exchange law, etc. Fields of temperature, pressure, velocity and volume fraction of phases were obtained at different ballast water mass flows. Dependence of wall temperature from mass flow of ballast water is constructed, that allows us to compare results of the experiment and mathematical modeling.