The purpose of this research was to determine the effectiveness of the reagent treatment of wastewater from breweries. The object of the study was the wastewater of the Samara brewery. To achieve this goal, a trial coagulation of the original wastewater of the brewery was carried out using six diff erent reagents. During the experiment, the optimal doses of each coagulant were determined. It was found experimentally that the maximum effi ciency of coagulation was 34 % in terms of COD. Comparative results of the reagent treatment with various coagulants showed that an increase in the reagent dose over 150 mg / l in terms of Me2O3 did not lead to an increase in the purifi cation effi ciency, however, the cost of purifi ed water signifi cantly increased. The research results were used in the development of a cleaning scheme for the brewery in Samara.