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The aim of the research is the reason of application of ketorol as an analgesic component of general anesthesia during endoscopic gynaecological surgery with regard to sterility. A retrospective analysis of medical history of 200 females at the age of 19–35 who underwent a surgery for sterility has been carried out. All the patients were divided into 4 groups (50 objects in each). In the first group ketamine anesthesia was applied, in the second group — dormicum-based ataralgesia, in the third group — neuroleptanalgesia, and in the fourth group – anesthesia by propofol together with preemptive analgesia by ketorol were applied. It was anesthesia risk of the first degree according to ASA classification. All the variants of anesthesia provided its adequacy. Among the patients from groups 1–3 28–40 % needed extra postsurgical analgesia, 8–12 % needed a postsurgical artificial lung ventilation period, 6–8 % had PONV. Аnalgesia by ketorol in complex with propofol provided adequate anesthesia during laparoscopic gynaecological operations with regard to sterility, it wasn’t followed by postoperative nausea or vomiting, it didn’t require extended postsurgical artificial lung ventilation or extra anesthetization