The review focuses on the clinical and epidemiological characteristics of herpes viral infection, in particular genital herpes. The current treatment options for recurrent genital herpes are presented. A detailed description of valaciclovir is given.

The article presents information about a survey of 394 students from medical university and non-specialized institutions in Novosibirsk, in order to analyze the level of awareness about risky sexual behavior and prevention of HIV infection and STIs. The obtained information indicates a lack of awareness among young people about HIV/STIs. Students showed low alertness about their own safety. There was revealed a high degree of communicative tolerance among students. It was established, that students have a sense of tolerance for the uncomfortable feelings of the partner during communication, and the lack of ability to hide their negative emotions about non-communicative qualities of the partner.

Bacterial vaginosis is an infectious non-inflammatory syndrome characterized by the replacement of the usual microflora by the polymicrobial associations of anaerobes and Gardnerella vaginalis. The review is devoted to current issues of this disease, including pathogenesis, clinical manifestations and approaches to laboratory diagnostics. Discussion issues of this disease related to the possibility of sexual transmission are discussed. Particular attention is paid to the factors causing the development of bacterial vaginosis. The classical concepts of diagnostic criteria for diagnosis are presented. Bacterial vaginosis is not characterized by the presence of a specific microorganism, but is the result of the formation of a bacterial biofilm on the epithelium of the vagina or foreskin. The main component of this biofilm is G. vaginalis. Bacterial vaginosis is caused by polymicrobial gardnerella biofilm, which can only be transferred as a whole (for example, with the help of key cells) only during sexual intercourse. Along with this, the authors discuss modern aspects related to the problem of microbial biofilm formation. In this regard, the authors propose to use a new term biofilm vaginosis, which more accurately reflects the essence of this problem. The modern possibilities of treating bacterial vaginosis are presented. The use of combined local therapy of nonspecific inflammatory processes of the vulvovaginal zone is becoming especially relevant at the present stage. The use of a local combination drug (Gainomax) with the widest possible spectrum of action allows doctors to achieve rapid relief of symptoms and high efficiency of therapy.

The main trends in the incidence of syphilis, including its late forms, are analysed in Novosibirsk in 20132017. It was found that during this period there was a trend to a decrease in the incidence of syphilis in Novosibirsk, but there was an increase in cases of detection of late forms of syphilis, in particular late latent syphilis and neurosyphilis, mainly in men at the age of 40 years and older. A unique clinical case demonstrating the complexity of differential diagnosis of neurosyphilis is also presented.

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