Introduction: A combination of lidocaine, epinephrine, and tetracaine (LET) is often used for surface anaesthesia in wound management in children. Several studies, mainly from the United States, showed that LET is as effective as lidocaine infiltration. However, reports on the LET are scarce in Japan. Therefore, this study evaluated the efficacy and safety of LET during wound management in children at the emergency department in Japan. Methods: This single-center retrospective descriptive study included pediatric patients (age ≤15) treated with wounds using the LET from April 2018 to March 2021. We collected data on patients' age and sex, length, and site of the wound, use of additional lidocaine infiltration, procedural sedation and analgesia (PSA), and adverse events. Results: A total of 312 patients were included in this study. Wound treatment was completed with only LET in 262 cases (84%), LET and lidocaine infiltration in 35 cases (11%), LET and PSA in 10 cases (3%), LET, lidocaine infiltration, and PSA in 5 cases (2%). Moreover, no adverse events were reported. Conclusion: Using the LET during wound management could be effective and safe in Japanese pediatric patients.

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